Detection and differentiation of coxiella burnetii in biological fluids
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United States of America Patent
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Nov 2, 1993
Issued Date -
N/A
app pub date -
Oct 23, 1989
filing date -
Nov 5, 1985
priority date (Note) -
Expired
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Abstract
Methods for detecting the presence of Coxiella burnetii in biological samples, as well as a method for differentiating strains of C. burnetii that are capable of causing acute disease from those strains capable of causing chronic disease are disclosed. The methods generally comprise treating cells contained within the biological sample to expose cellular DNA, and hybridizing the cellular DNA with a DNA probe containing DNA sequences that specifically hybridize with C. burnetii DNA of strains associated with the capacity to cause acute or chronic disease.
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