Process for producing nucleosides
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United States of America Patent
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Nov 2, 1993
Grant Date -
N/A
app pub date -
Oct 26, 1990
filing date -
Feb 28, 1989
priority date (Note) -
Expired
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Abstract
The present invention concerns a process for producing nucleosides by carrying out the reaction of a base donor, a saccharide residue donor and a phosphoric acid donor by the use of an enzyme preparation containing nucleoside phosphorylase, thereby forming an N-glycosidic bond between the base moiety of the base donor and the saccharide moiety of the saccharide residue donor, which comprises using, as the enzyme preparation containing nucleoside phosphorylase, a preparation derived from the cells of one or more kinds of microorganisms belonging to thermophiles of the genus Bacillus and having high nucleoside phosphorylase activity per unit cell weight.
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