Cholesterol lowering compounds

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United States of America Patent

PATENT NO 5258401
SERIAL NO

07938981

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are compounds of structural formula (I) ##STR1## which are useful as cholesterol lowering agents. These compounds are also useful as inhibitors of squalene synthase, inhibitors of fungal growth, inhibitors of farnesyl-protein transferase and farnesylation of the oncogene protein Ras. These compounds are also useful in the treatment of cancer.

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Patent Owner(s)

Patent OwnerAddress
MERCK & CO INC126 EAST LINCOLN AVENUE RAHWAY NEW JERSEY UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berger, Gregory D Belle Mead, NJ 9 204
Marquis, Jr Robert W Iselin, NJ 10 33
Robichaud, Albert J Stirling, NJ 33 1778
Scolnick, Edward M Wynnewood, PA 14 252

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