Photolabile reagents for incorporation into oligonucleotide chains

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United States of America Patent

PATENT NO 5258506
SERIAL NO

07398711

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Abstract

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Novel photolabile photochemical reagents are disclosed. The reagents are useful in a variety of biochemical and chemical contexts, including nucleic hybridization assays and chemical phosphorylation of hydroxyl-containing compounds. The reagents are particularly useful for introducing cleavable sites into oligonucleotide or polynucleotide chains, i.e., sites which are cleavable upon photolysis. The reagents are also useful in both 5'- and 3'-phosphorylation of oligonucleotide or polynucleotide chains.

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Patent Owner(s)

Patent OwnerAddress
CHIRON DIAGNOSTICS CORPORATION333 CONEY STREET EAST WALPOLE MA 02032 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Horn, Thomas Berkeley, CA 63 5411
Urdea, Michael S Alamo, CA 71 6102

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