Method for obtaining bone marrow free of tumor cells using transforming growth factor .beta.3

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United States of America Patent

PATENT NO 5262319
SERIAL NO

07543341

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides (1) an antibody which (a) specifically binds to human TGF-.beta.3 and (b) exhibits substantially no cross reactivity with TGF-.beta.1 or TGF-.beta.2 and (2) antibodies directed against the pro region of the TGF-.beta. precursor. Further, this invention provides a pharmaceutical composition comprising the pro region of the TGF-.beta. precursor. Also, this invention provides methods for diagnosing, detecting and treating subjects suffering from disorders associated with TGF-.beta.3.

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Patent Owner(s)

Patent OwnerAddress
OSI PHARMACEUTICALS INC41 PINELAWN ROAD MELVILLE NY 11747

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dijke, Peter T Port Washington, NY 1 31
Foulkes, J Gordon Huntington, NY 35 516
Haley, John D Great Neck, NY 34 904
Iwata, Kenneth K Westbury, NY 10 82

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