.alpha.-1-antichymotrypsin, analogues and methods of production

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United States of America Patent

PATENT NO 5266465
SERIAL NO

07735322

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Abstract

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The invention provides .alpha.-1-antichymotrypsin and protein preparations comprising human .alpha.-1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human .alpha.-1-antichymotrypsin. The invention also provides methods for producing .alpha.-1-antichymotrypsin. The invention further provides analogues of .alpha.-1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.

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Patent Owner(s)

Patent OwnerAddress
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA THE A CORP OF PA133 SOUTH 36TH ST STE 419 PHILADELPHIA PA 19104-3246

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cooperman, Barry S Penn Valley, PA 13 37
Rubin, Harvey Philadelphia, PA 95 3084
Schecter, Norman Philadelphia, PA 1 9
Wang, Zhi M Philadelphia, PA 5 43

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