PDGF receptor blocking peptides
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United States of America Patent
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Dec 7, 1993
Issued Date -
N/A
app pub date -
May 6, 1991
filing date -
Dec 8, 1988
priority date (Note) -
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Abstract
Methods and compositions are provided for treating several acute disease states associated with smooth muscle cell proliferation as well as the chronic process of atherogenesis utilizing oligopeptides corresponding to regions of the PDGF receptor protein. The oligopeptides can be used to block PDGF binding and activation for numerous applications, and can serve as immunogens to raise receptor-specific antibodies.
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