Methods for reducing bone loss using centchroman derivatives

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United States of America Patent

PATENT NO 5280040
SERIAL NO

08029729

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods and pharmaceutical compositions for reducing bone loss are disclosed. 3,4-diarylchromans and their pharmaceutically acceptable salts are formulated into medicaments for the treatment of bone loss due to osteoporosis or other conditions. An exemplary 3,4-diarylchroman is centchroman (3,4-trans-2,2-dimethyl-3-phenyl-4-[p-(beta-pyrrolidinoethoxy)phenyl]-7-methoxy-chroman). Formulations include tablets and other forms suitable for oral administration and controlled-release subdermal implants.

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Patent Owner(s)

Patent OwnerAddress
ZYMOGENETICS INC1201 EASTLAKE AVENUE EAST SEATTLE WA 98102

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bain, Steven D Seattle, WA 2 99
Labroo, Virender M Mill Creek, WA 21 290
Piggott, James R Bothell, WA 12 191

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