Method for detecting the .gamma.,.delta. T cell receptor

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United States of America Patent

PATENT NO 5286653
SERIAL NO

06881825

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Abstract

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The present invention provides purified polypeptides which comprise at least a portion of a .delta.T cell receptor polypeptide, a .gamma.T cell receptor polypeptide or a .gamma.,.delta. T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.

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Patent Owner(s)

Patent OwnerAddress
ASTRA ABSWEDISH SODERTALJE SODERTALJE STOCKHOLM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brenner, Michael B Ashland, MA 36 437
Ip, Stephen H Framingham, MA 26 498
Krangel, Michael S Newtonville, MA 7 52
Seidman, Jonathan Milton, MA 8 45
Strominger, Jack L Lexington, MA 52 1169

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