Pyridyl compounds and pharmaceutical compositions containing these compounds
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United States of America Patent
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Feb 15, 1994
Issued Date -
N/A
app pub date -
Jan 19, 1993
filing date -
Nov 22, 1990
priority date (Note) -
Expired
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Abstract
New pyridyl derivatives of the formula ##STR1## wherein R.sub.1 to R.sub.6, A, X and n are as defined herein, the enantiomers thereof, the cis- and trans-isomers thereof if R.sub.4 and R.sub.5 together represent a carbon-carbon bond, and the addition salts thereof. The new pyridyl derivatives have antithrombotic activity and thromboxane-mediated activities. The new compounds are also simultaneously thromboxane antagonists (TRA) and thromboxane synthesis inhibitors (TSH). They also have an effect on PGE.sub.2 -production.
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