Topical drug delivery with polyoxyalkylene polymer thermoreversible gels adjustable for pH and osmolality
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United States of America Patent
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Mar 29, 1994
Issued Date -
N/A
app pub date -
Jun 9, 1992
filing date -
May 1, 1990
priority date (Note) -
Expired
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Abstract
Iso-osmotic, hyperosmotic, or hypo-osmotic, pH balanced, thermoreversible gels are ideal medical devices or vehicles for drug delivery to the skin of a mammal. The osmolality in the gel state can be calculated by assuming that a polyoxyalkylene block copolymer or polyether present in said gel does not contribute to the osmolality in the gel state, although it does contribute to the measured osmolality in the liquid state.
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