US Patent No: 5,302,172

Number of patents in Portfolio can not be more than 2000

Method and composition for iontophoresis

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Abstract

The invention discloses methods and compositions for enhanced iontophoretic delivery of active agents. The compositions are pharmaceutically acceptable compositions for iontophoretic delivery comprising a delivery enhancing amount of a vasodilator and active agent. Methods comprise adding a delivery enhancing amount of a vasodilator to an active agent and delivering by iontophoresis.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
NORTH CAROLINA STATE UNIVERSITYRALEIGH, NC833
VYTERIS, INC.FRANKLIN LAKES, NJ68
NORTH CAROLINA STATE UNIVERSITY OFFICE OF THE VICE CHANCELLOR FOR RESEARCH, OUTREACH AND EXTENSIONRALEIGH, NC2

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Riviere, Jim E Raleigh, NC 7 61
Sage, Jr Burton H Vista, CA 28 869

Cited Art

Patent Info (Count) # Cites Year
 
ALZA CORPORATION (4)
5,047,007 Method and apparatus for pulsed iontophoretic drug delivery 104 1989
5,084,008 Iontophoresis electrode 56 1989
5,084,006 Iontopheretic delivery device 66 1990
5,057,072 Iontophoresis electrode 58 1990
 
MEDTRONIC, INC. (2)
4,406,658 Iontophoretic device with reversible polarity 137 1981
4,820,263 Apparatus and method for iontophoretic drug delivery 70 1987
 
Cyclex, Inc. (1)
5,068,226 Pharmaceutical preparations containing cyclodextrins and their use in iontophoretic therapies 27 1990
 
Drug Delivery Systems Inc. (1)
5,088,977 Electrical transdermal drug applicator with counteractor and method of drug delivery 38 1988
 
ELAN TRANSDERMAL LIMITED (1)
5,135,480 Transdermal drug delivery device 100 1990
 
PFIZER INC. (1)
5,023,085 Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals 47 1989
 
TRUSTEES OF BOSTON UNIVERSITY (1)
4,702,732 Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands 195 1986
 
UNIVERSITY OF UTAH (1)
4,752,285 Methods and apparatus for iontophoresis application of medicaments 122 1986
 
VYTERIS, INC. (1)
4,950,229 Apparatus for an electrode used for iontophoresis 42 1989

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
ALZA CORPORATION (6)
5,990,179 Composition and method of enhancing electrotransport agent delivery 20 1995
5,622,530 Method and apparatus for controlled environment electrotransport 19 1995
6,004,309 Method and apparatus for controlled environment electrotransport 33 1997
6,246,904 Electrotransport drug delivery reservoirs containing inert fillers 10 1997
6,295,469 Formulation for electrically assisted delivery of lidocaine and epinephrine 14 1997
6,289,241 Method and apparatus for controlled environment electrotransport 30 1998
 
BECTON DICKINSON RESEARCH CENTER (2)
5,961,483 Iontophoretic delivery of cell adhesion inhibitors 37 1997
5,935,598 Iontophoretic delivery of cell adhesion inhibitors 44 1997
 
ENCORE MEDICAL ASSET CORPORATION (2)
5,840,056 Iontophoresis electrode 15 1995
5,788,666 Iontophoresis electrode 37 1995
 
IMPLEMED, INC. (2)
6,060,000 Iontophoretic material containing carbon and metal granules 4 1998
6,287,484 Iontophoretic material 14 1999
 
ACIONT, INC. (1)
6,553,255 Use of background electrolytes to minimize flux variability during iontophoresis 15 2000
 
BATTELLE MEMORIAL INSTITUTE (1)
7,099,713 Skin conduction and transport systems 0 2003
 
BRIDGE BLOOD TECHNOLOGIES LLC, NEW YORK LIMITED LIABILITY COMPANY (1)
5,759,564 Iontophoretic material 22 1996
 
EMORY UNIVERSITY (1)
6,375,990 Method and devices for transdermal delivery of lithium 4 2000
 
INTRABRAIN INTERNATIONAL NV (1)
7,033,598 Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal 6 2002
 
MINNESOTA HIGH-TECH RESOURCES, LLC (1)
7,764,993 Iontophoretic delivery patch 0 2003
 
NORTH CAROLINA STATE UNIVERSITY (1)
5,620,416 Methods of using topical agents with systemically administered active agents 3 1995
 
The Penn State Research Foundation (1)
5,833,647 Hydrogels or lipogels with enhanced mass transfer for transdermal drug delivery 34 1995
 
TTI ELLEBEAU, INC. (1)
7,848,801 Iontophoretic systems, devices, and methods of delivery of active agents to biological interface 0 2006
 
Other [Check patent profile for assignment information] (3)
5,954,675 Method of ultrasonic therapy 31 1997
6,650,934 Polymeric foam reservoirs for an electrotransport delivery device 3 1997
6,730,691 Uses of alpha adrenergic blocking agents 1 2000