Method of laser-induced tissue necrosis in carotenoid-containing skin structures
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United States of America Patent
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Apr 19, 1994
Grant Date -
N/A
app pub date -
Mar 12, 1993
filing date -
Mar 12, 1993
priority date (Note) -
Expired
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Abstract
A method for treating dermatological organ disorders and skin lesions in a mammal through the use of directed, pulsed laser light is described. The dermatological disorders are characterized by an increase in concentration of potential photodynamic chemical compounds like carotenoid compounds, and especially the carotenoid beta-carotene, compared to normal skin. Pulsed dye laser light of a time and duration specific for maximal absorption by a carotenoid compound like beta-carotene is directed at the regions of carotenoid accumulation within a skin disorder. Thermal coagulation necrosis of the carotenoid-accumulating skin region results, though thermal damage to surrounding tissue is limited in amount.
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