Diphenylmethyl piperazine derivatives
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United States of America Patent
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Apr 19, 1994
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N/A
app pub date -
Mar 2, 1993
filing date -
Jul 10, 1990
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Abstract
Novel diphenylmethyl piperazine derivatives of this invention have a chemical structure represented by the following Formula [I]: ##STR1## wherein R represents ##STR2## The compounds have an effect of inhibiting the overcontraction and overextension of the myocardium without being accompanied by a myocardium-inhibiting effect. By using the novel diphenylmethyl piperazine derivatives as an effective ingredient, it is possible to obtain a myocardial necrosis inhibitor which can protect against myocardial necrosis, and a drug for the treatment and prevention of acute myocardial infarction.
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