Pharmaceutical composition for rapid suspension in water
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United States of America Patent
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-
Apr 26, 1994
Grant Date -
N/A
app pub date -
Mar 3, 1992
filing date -
Jul 11, 1990
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The invention provides a solid pharmaceutical composition for addition to water to produce a suspension of a drug comprising (a) a drug which is substantially water-insoluble or microencapsulated; (b) a thickening or suspending agent; (c) a pharmaceutically acceptable acid; (d) a pharmaceutically acceptable carbonate or bicarbonate; characterised in that the weight ratio of c+d:b is from 1:1.5 to 1:15 and the amount of c+d is sufficient to obtain rapid hydration of the thickening or suspending agent (b) when the composition is mixed with water such that a homogeneous suspension of the drug is obtained within 30 seconds. A method for preparing the composition is also described.
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