Fullerene coated surfaces and uses thereof
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United States of America Patent
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May 10, 1994
Grant Date -
N/A
app pub date -
Jun 22, 1992
filing date -
Jun 22, 1992
priority date (Note) -
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Abstract
Substrates having a surface coated with fullerene and a substance attached thereto are disclosed. Cell culture substrates having a fullerene-coated surface are useful in methods of growing cells on the fullerene-coated surface. Methods of preparing cell culture substrates for cell attachment and growth by coating a surface with fullerene are provided. Cells can be grown on a fullerene-coated surface in the presence of a substance such as a cytokine, growth hormone or a drug, to evaluate the interaction between the substance and the cells. Methods for increasing cell membrane premability and for introducing a substance, such as a DNA or RNA vector, into a cell are also provided.
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