US Patent No: 5,314,476

Number of patents in Portfolio can not be more than 2000

Demineralized bone particles and flowable osteogenic composition containing same

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ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

Demineralized bone particles having a median length to median thickness ratio of at least about 10:1 are incorporated in an osteogenic composition useful for repairing bone defects.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
OSTEOTECH INVESTMENT CORPORATIONSHREWSBURY, NJ21
WARSAW ORTHOPEDIC, INC.WARSAW, IN1462

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Prewett, Annamarie B Little Silver, NJ 9 926
Stikeleather, Roger C Doylestown, PA 7 615

Cited Art

Patent Info (Count) # Cites Year
 
BAXTER INTERNATIONAL INC. (1)
5,053,049 Flexible prostheses of predetermined shapes and process for making same 107 1985
 
GENDLER FAMILY LIMITED PARTNERSHIP (1)
4,932,973 Cartilage and bone induction by artificially perforated organic bone matrix 135 1988
 
GENSCI ORTHOBIOLOGICS, INC. (1)
4,472,840 Method of inducing osseous formation by implanting bone graft material 205 1982
 
OSTEOTECH INVESTMENT CORPORATION (1)
5,073,373 Flowable demineralized bone powder composition and its use in bone repair 166 1989

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
WARSAW ORTHOPEDIC, INC. (38)
5,507,813 Shaped materials derived from elongate bone particles 240 1993
5,899,939 Bone-derived implant for load-supporting applications 261 1998
6,123,731 Osteoimplant and method for its manufacture 159 1998
6,436,138 Process for producing flexible sheets from demineralized, elongate, bone particles 17 1998
6,294,187 Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same 156 1999
6,294,041 Method for an osteoimplant manufacture 89 1999
6,843,807 Osteoimplant 16 2000
7,726,319 Method for removal of water associated with bone while diminishing the dimensional changes associated with lyophilization 0 2000
6,638,310 Intervertebral spacer and implant insertion instrumentation 31 2000
6,616,698 Bone graft and guided bone regeneration method 19 2001
6,855,167 Spinal intervertebral implant, interconnections for such implant and processes for making 45 2001
7,323,193 Method of making demineralized bone particles 5 2001
6,696,073 Shaped load-bearing osteoimplant and methods of making same 141 2002
7,163,691 Bone graft 19 2002
7,833,255 Bone fasteners and method for stabilizing vertebral bone facets using the bone fasteners 3 2002
7,662,185 Intervertebral implants 1 2003
8,133,421 Methods of making shaped load-bearing osteoimplant 0 2003
7,413,576 Biocompatible osteogenic band for repair of spinal disorders 10 2004
7,726,002 Processes for making spinal intervertebral implant, interconnections for such implant 0 2004
8,328,876 Bone matrix compositions and methods 0 2004
8,333,985 Non-glycerol stabilized bone graft 0 2005
7,780,708 Implant retaining device 3 2005
7,838,022 Malleable implants containing demineralized bone matrix 1 2006
7,771,741 Demineralized bone matrix devices 0 2006
8,268,008 Osteoimplants and methods for their manufacture 0 2006
7,959,941 Bone graft comprising a demineralized bone matrix and a stabilizing agent 0 2007
7,939,108 Method of making demineralized bone particles 0 2007
8,372,157 Joint revision implant 0 2008
8,039,016 Malleable implants containing demineralized bone matrix 0 2008
8,357,384 Bone matrix compositions and methods 0 2008
7,799,076 Biocompatible osteogenic band for repair of spinal disorders 8 2008
8,202,539 Demineralized bone matrix compositions and methods 0 2008
8,002,813 Volume maintaining osteoinductive/osteoconductive compositions 0 2009
8,431,147 Malleable implants containing demineralized bone matrix 0 2010
8,282,953 Malleable implants containing demineralized bone matrix 0 2010
8,252,056 Biocompatible osteogenic band for repair of spinal disorders 0 2010
8,197,474 Volume maintaining osteoinductive/osteoconductive compositions 0 2011
8,435,566 Demineralized bone matrix compositions and methods 0 2012
 
MUSCULOSKELETAL TRANSPLANT FOUNDATION (22)
6,030,635 Malleable paste for filling bone defects 96 1998
6,326,018 Flexible sheet of demineralized bone 33 1999
6,437,018 Malleable paste with high molecular weight buffered carrier for filling bone defects 46 2000
6,458,375 Malleable paste with allograft bone reinforcement for filling bone defects 55 2000
6,432,436 Partially demineralized cortical bone constructs 30 2000
6,911,212 Malleable putty and flowable paste with allograft bone having residual calcium for filling bone defects 35 2001
RE38522 Malleable paste for filling bone defects 18 2002
6,548,080 Method for partially demineralized cortical bone constructs 1 2002
7,045,141 Allograft bone composition having a gelatin binder 23 2002
7,019,192 Composition for filling bone defects 7 2002
7,067,123 Glue for cartilage repair 11 2003
7,901,457 Cartilage allograft plug 6 2003
RE39587 Malleable paste for filling bone defects 10 2004
7,488,348 Cartilage allograft plug 8 2005
7,879,103 Vertebral disc repair 0 2006
7,815,926 Implant for articular cartilage repair 2 2006
7,837,740 Two piece cancellous construct for cartilage repair 4 2007
RE42208 Glue for cartilage repair 3 2008
8,221,500 Cartilage allograft plug 0 2008
8,435,551 Cancellous construct with support ring for repair of osteochondral defects 0 2009
RE43258 Glue for cartilage repair 0 2010
8,292,968 Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles 0 2011
 
GMEDELAWARE 2 LLC (19)
8,163,017 Facet arthroplasty devices and methods 0 2003
8,092,532 Facet arthroplasty devices and methods 0 2003
8,070,811 Facet arthroplasty devices and methods 0 2003
8,066,771 Facet arthroplasty devices and methods 0 2003
7,087,084 Method for replacing a natural facet joint with a prosthesis having an artificial facet joint structure 112 2003
8,187,303 Anti-rotation fixation element for spinal prostheses 0 2004
7,691,145 Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces 13 2004
7,608,104 Prostheses, tools and methods for replacement of natural facet joints with artifical facet joint surfaces 2 2004
7,674,293 Crossbar spinal prosthesis having a modular design and related implantation methods 26 2005
8,398,681 Adjacent level facet arthroplasty devices, spine stabilization systems, and methods 0 2005
7,406,775 Implantable orthopedic device component selection instrument and methods 24 2005
8,066,740 Facet joint prostheses 0 2005
8,221,461 Crossbar spinal prosthesis having a modular design and systems for treating spinal pathologies 0 2005
7,608,106 Facet arthroplasty devices and methods 6 2006
7,290,347 Facet joint prosthesis measurement and implant tools 19 2006
8,231,655 Prostheses and methods for replacement of natural facet joints with artificial facet joint surfaces 0 2006
7,914,556 Arthroplasty revision system and method 0 2006
8,425,557 Crossbar spinal prosthesis having a modular design and related implantation methods 0 2007
8,409,254 Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces 0 2008
 
SYNTHES USA, LLC (14)
6,660,038 Skeletal reconstruction cages 84 2001
6,986,788 Intervertebral allograft spacer 23 2001
6,855,169 Demineralized bone-derived implants 18 2001
6,776,800 Implants formed with demineralized bone 20 2001
7,608,113 Demineralized bone implants 9 2003
7,014,659 Skeletal reconstruction cages 10 2003
7,232,464 Intervertebral implant 22 2004
7,226,482 Multipiece allograft implant 10 2004
7,300,465 Intervertebral allograft spacer 4 2005
7,846,207 Intervertebral implant 5 2005
7,601,173 Multipiece allograft implant 13 2007
7,618,456 Intervertebral implant 11 2007
7,753,963 Demineralized bone-derived implants 0 2008
7,862,616 Intervertebral implant 7 2009
 
WRIGHT MEDICAL TECHNOLOGY, INC. (10)
7,371,408 Bone graft substitute composition 2 1999
7,371,409 Bone graft substitute composition 1 2001
7,371,410 Bone graft substitute composition 1 2002
6,652,887 Bone graft substitute composition 14 2002
7,211,266 Bone graft substitute composition 2 2003
7,291,179 Bone graft substitute composition 1 2003
7,507,257 Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects 0 2004
7,250,550 Synthetic bone substitute material 10 2004
7,766,972 Synthetic, malleable bone graft substitute material 0 2007
7,658,768 Bone graft substitute composition 8 2007
 
NUORTHO SURGICAL, INC. (7)
7,771,422 Methods and devices for electrosurgery 11 2004
7,819,861 Methods for electrosurgical electrolysis 5 2004
7,445,619 Devices for electrosurgery 7 2005
7,955,296 Biologically enhanced irrigants 0 2006
7,713,269 Devices for electrosurgery 3 2008
7,819,864 Electrosurgery devices 5 2009
8,235,979 Interfacing media manipulation with non-ablation radiofrequency energy system and method 0 2010
 
BIOMET MANUFACTURING CORP. (6)
5,674,224 Bone mulch screw assembly for endosteal fixation of soft tissue grafts and method for using same 98 1994
6,565,884 Bone graft material incorporating demineralized bone matrix and lipids 15 2001
7,357,947 Bone graft material incorporating demineralized bone matrix and lipids 2 2003
7,678,385 Irradiated implantable bone material 1 2004
7,670,384 Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone 5 2006
7,976,861 Irradiated implantable bone material 0 2010
 
ORTHOCON, INC. (5)
8,105,628 Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects 1 2004
7,989,000 Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects 0 2004
7,955,616 Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects 0 2005
8,337,879 Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects 0 2011
8,309,131 Absorbable putty-like implants and methods for their use for mechanical hemostasis of bone and for the treatment of osseous defects 0 2011
 
KENSEY NASH BVF TECHNOLOGY, LLC (4)
8,435,306 Devices and methods for treating defects in the tissue of a living being 0 2010
8,425,619 Devices and methods for treating defects in the tissue of a living being 0 2010
8,419,802 Devices and methods for treating defects in the tissue of a living being 0 2011
8,163,032 Devices and methods for treating defects in the tissue of a living being 0 2011
 
AGNOVOS HEALTHCARE, LLC (2)
7,754,246 Composite bone graft substitute cement and articles produced therefrom 1 2006
8,025,903 Composite bone graft substitute cement and articles produced therefrom 0 2007
 
DOCTORS RESEARCH GROUP, INC. (2)
7,964,207 Methods of performing medical procedures that promote bone growth, method of making compositions that promote bone growth, and apparatus for use in such methods 0 2005
8,211,458 Methods of performing medical procedures that promote bone growth, methods of making compositions that promote bone growth, and apparatus for use in such methods 0 2011
 
CHILDREN'S MEDICAL CENTER CORPORATION (1)
6,165,487 Methods and compositions for programming an organic matrix for remodeling into a target tissue 16 1998
 
DANEK MEDICAL, INC. (1)
7,981,156 Bone grafts 0 2004
 
EBI, LLC (1)
7,621,963 Composite bone graft material 8 2006
 
ETEX CORPORATION (1)
7,582,309 Cohesive demineralized bone compositions 1 2002
 
GENDLER FAMILY LIMITED PARTNERSHIP (1)
6,576,249 Bone putty and method 19 2000
 
LIFENET HEALTH (1)
7,494,811 In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby 1 2004
 
NORIAN CORPORATION (1)
6,334,891 Paste compositions capable of setting into carbonated apatite 18 1999
 
OSPREY BIOMEDICAL, INC. (1)
8,043,377 Implantable intervertebral fusion device 0 2006
 
OSTEOTECH, INC. (1)
6,752,831 Biocompatible osteogenic band for repair of spinal disorders 130 2000
 
SMITH & NEPHEW, INC. (1)
8,308,340 Composite mixer 0 2005
 
SPINEOLOGY, INC. (1)
7,959,683 Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation 9 2007
 
WBK, INC. (1)
5,788,976 Method for effecting bone repair 30 1996
 
ZIMMER ORTHOBIOLOGICS, INC. (1)
6,679,918 Implantable putty material 18 1998
 
ZIMMER SPINE, INC. (1)
D580551 Spinal implant 3 2007
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
6,372,257 Compositions and methods for forming and strengthening bone 28 2000