1-7 disubstituted xanthine derivatives having antiasthmatic activity, their physiologically acceptable salts, pharmaceutical compositions containing them and process for their preparation
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United States of America Patent
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May 24, 1994
Grant Date -
N/A
app pub date -
Nov 17, 1992
filing date -
May 24, 1990
priority date (Note) -
Expired
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Abstract
Xanthine derivatives having antiasthmatic activity are disclosed which have the following formula: ##STR1## where R is a linear or branched alkyl chain group of from one to six carbon atoms, R.sub.1 is a linear or branched alkyl or hydroxyalkyl group of from one to six carbon atoms. However, if R is methyl, then R.sub.1 is not methyl, ethyl or propyl; if R is ethyl, then R.sub.1 is not methyl or ethyl; and if R is methyl or n-butyl, then R.sub.1 is not 2-hydroxypropyl. Also disclosed are pharmaceutical compositions containing such xanthine derivatives.
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