Process for the preparation of a tablet or dragee composition containing a heat-, light- and moisture-sensitive active ingredient having monoclinic crystal structure

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United States of America Patent

PATENT NO 5322698
SERIAL NO

07849067

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Abstract

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The invention relates to a process for the preparation of a tablet or dragee composition containing a moisture-, heat- and light-sensitive compounds having monoclinic crystalline structure as active ingredients, which comprises homogenizing the active ingredient with 0.2 to 1.5 parts by weight of an anhydrous alkaline earth metal salt and 0.5 to 2.5 parts by weight of microcrystalline cellulose calculated for the active ingredient and optionally with one or more pharmaceutically acceptable carrier(s) and/or additive(s) and compressing the homogeneous mixture obtained to tablets in a manner known per se and, if desired, coating the tablet thus obtained in a manner known per se.

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Patent Owner(s)

  • BIOGAL GYOGYSZERGYAR RT.;TEVA GYOGYSZERGYAR RESZVENYTARSASAG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bacsa, Gyorgy Debrecen, HU 7 69
Beke, Katalin Debrecen, HU 1 25
Biblo, Margit Budapest, HU 1 25
Bobak, Dorottya Budapest, HU 1 25
Jancso, Sandor Debrecen, HU 8 129
Kovacs, Istvan Debrecen, HU 23 226
Lango, Jozsef Budapest, HU 4 27
Marossy, Katalin Debrecen, HU 4 27
Mathe, Tibor Debrecen, HU 3 57
Orban, Erno Budapest, HU 5 138
Simo, Margit Budapest, HU 1 25
Szendrei, Levente Debrecen, HU 1 25
Szilagyi, Judit Debrecen, HU 2 38

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