Importance

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Abstract

Controlled release pharmaceutical preparations are prepared by homogenizing an organic or inorganic pharmaceutical active substance such as an opium alkaloid or its salts, an opium antagonist or its salts, an aliphatic or aromatic amine derivative or its salts, a phenolate type medicament, or Zn, Fe, Mg, K, Na salts, a fatty acid or its salt necessary to achieve a continuous phase transfer and an ethylene vinyl acetate copolymer and formulating the resulting homogeneous mixture by a) direct compressing or b) admixing with a solvent or c) using a second, auxiliary polymer. The preparations are suitable for oral or rectal administration or for tissue implantation.

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First Claim