Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding

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United States of America Patent

PATENT NO 5326856
SERIAL NO

07866375

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Abstract

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This invention relates to chelating agents useful for coupling metal ions to biologically active molecules. In particular, isothiocyanate derived thiocarbonyls for chelating metals such as technetium are provided that can be conjugated to a targeting molecule such as an antibody, a peptide or a protein.

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Patent Owner(s)

Patent OwnerAddress
CYTOGEN CORPORATION A CORPORATION OF DELAWARE600 COLLEGE ROAD EAST-CN 5308 PRINCETON FORRESTAL CENTER PRINCETON NJ 08540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Belinka, Jr Benjamin A Kendall Park, NJ 11 472
Coughlin, Daniel J Robbinsville, NJ 22 1057

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