MCC gene (mutated in colorectal cancer) used for diagnosis of cancer in humans

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United States of America Patent

PATENT NO 5330892
SERIAL NO

07670611

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Abstract

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A new human gene termed MCC is disclosed. Methods and kits are provided for assessing mutations of the MCC gene in human tissues and body samples. Gross rearrangement and point mutations in MCC are observed in human tumor cells. MCC is expressed in most normal tissues. These results suggest that MCC is a tumor suppressor.

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Patent Owner(s)

Patent OwnerAddress
CANCER INSTITUTE THE A CORPORATION OF JAPAN37-1 1-CHOME KAMI-IKEBUKURO TOSHIMA-KU TOKYO 170 JAPAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kinzler, Kenneth W Baltimore, MD 296 5437
Nakamura, Yusuke Tokyo, JP 416 3218
Vogelstein, Bert Baltimore, MD 338 7135
White, Raymond Salt Lake City, UT 18 249

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