Glycoprotein isolated from ganoderma having immunosuppressive activity
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United States of America Patent
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Aug 2, 1994
Grant Date -
N/A
app pub date -
Apr 28, 1988
filing date -
Apr 28, 1987
priority date (Note) -
Expired
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Abstract
Disclosed herein is a novel glycoprotein derived from Ganoderma mycelia. The glycoprotein is free of human hemagglutination ability, and has immunosuppressive activities and a molecular weight of 16,000-18,000 as measured by SDS gel electrophoresis or 12,000-16,000 as measured by tricin-SDS gel electrophoresis. The glycoprotein is produced by culturing Ganoderma mycelia, extracting the resultant Ganoderma mycelia with an aqueous solvent, and then purifying the resultant extract. An immunosuppressive agent containing an effective amount of the glycoprotein is also disclosed.
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