Dopamine receptor ligands and imaging agents

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United States of America Patent

PATENT NO 5334728
SERIAL NO

07957259

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Abstract

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Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofuran, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain retention and in vivo stability.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIAPHILADELPHIA PA 19104-6283

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kung, Hank F Wynnewood, PA 52 443
Murphy, Raymond Philadelphia, PA 22 610

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