Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof

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United States of America Patent

PATENT NO 5338872
SERIAL NO

08005229

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Abstract

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A process for the preparation of a 10-desacetoxy and 10-desoxy tetracyclic taxane in which a tetracyclic taxane having a C10 hydroxy or acetoxy substituent is reacted with samarium diiodide.

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Patent Owner(s)

Patent OwnerAddress
FLORIDA STATE UNIVERSITY2035 EAST PAUL DIRAC DRIVE 109 HERB MORGAN BUILDING TALLAHASSEE FL 32310 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Holton, Robert A Tallahassee, FL 134 2437
Somoza, Carmen Tallahassee, FL 20 196

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