Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
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United States of America Patent
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Oct 4, 1994
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N/A
app pub date -
Oct 2, 1991
filing date -
Jun 10, 1991
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Abstract
Disclosed are methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides. Specifically, in the disclosed methods, sialyltransferase is activated to transfer an analogue of sialic acid, employed as its CMP-nucleotide derivative, to an oligosaccharide glycoside. The analogue of sialic acid and the oligosaccharide employed in this method are selected to be compatible with the sialyltransferase employed.
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