Compositions containing salts of bile acid-aminosalicylate conjugates
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United States of America Patent
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Oct 4, 1994
Grant Date -
N/A
app pub date -
Mar 8, 1993
filing date -
Mar 8, 1993
priority date (Note) -
Expired
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Abstract
Disclosed are compositions containing bile acid-aminosalicylate conjugates having the formula, or a pharmaceutically acceptable salt thereof ##STR1## wherein R.sub.1 is OH either the .alpha. or the .beta. position; R.sub.2 is OH; R.sub.3 is H or OH; and R.sub.4 is H or acetyl, the process for their preparation and method of treating/preventing gastrointestinal disorders, impaired liver function, autoimmune diseases of the liver and biliary tract, colon cancer, inflammatory bowel diseases, Crohn's disease, cystic fibrosis, dissolving gallstones, and regulating dietary cholesterol absorption by administering said compositions to a mammal in need of such treatment.
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