APC gene and nucleic acid probes derived therefrom

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United States of America Patent

PATENT NO 5352775
SERIAL NO

07741940

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous polyposis patients as well as in sporadic colorectal cancer patients. APC is expressed in most normal tissues. These results suggest that APC is a tumor suppressor.

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Patent Owner(s)

Patent OwnerAddress
ZENECA LIMITEDIMPERIAL CHEMICAL HOUSE 9 MILLBANK LONDON SW1P 3JF

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albertsen, Hans Salt Lake City, UT 17 447
Anand, Rakesh Cheshire, GB2 15 488
Carlson, Mary Salt Lake City, UT 9 482
Groden, Joanna Salt Lake City, UT 12 485
Hedge, Philip J Cheshire, GB2 1 108
Joslyn, Geoff Salt Lake City, UT 9 482
Kinzler, Kenneth Baltimore, MD 28 964
Markham, Alexander F Cheshire, GB2 2 213
Nakamura, Yusuke Tokyo, JP 416 3218
Thliveris, Andrew Salt Lake City, UT 8 440
Vogelstein, Bert Baltimore, MD 338 7135
White, Raymond L Salt Lake City, UT 16 527

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