Method and apparatus for optical measurement of bilirubin in tissue
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United States of America Patent
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Oct 11, 1994
Grant Date -
N/A
app pub date -
Jan 17, 1992
filing date -
Jan 17, 1992
priority date (Note) -
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Abstract
A method and apparatus for the determination of bilirubin concentration in tissue such as skin, particularly neonatal skin. Light reflected from the skin under test is analyzed to determine bilirubin concentration in the skin, corrected for maturity-dependent optical properties of the skin, the amount of melanin in the skin and the amount of blood in the skin. Reflected red to infrared light is used to determine maturity-dependent optical properties, reflected red light is used to determine melanin content, and reflected yellow-orange light is used to determine the amount of blood in the skin. Then, these quantities are used, in combination with reflected blue light, to calculate cutaneous bilirubin concentration.
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