Recombinant modified thermostable NAD-dependent dehydrogenases and process for their production
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United States of America Patent
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Oct 11, 1994
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N/A
app pub date -
Oct 24, 1991
filing date -
Mar 8, 1989
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Expired
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Abstract
A recombinant thermophilic NAD-dependent dehydrogenase having a hydrophobic amino acid at position 104 and/or 102. The enzymes are effective in catalysing the dehydrogenation of homologues of pyruvic acid of formula CnH.sub.2n+1 COCOOH, wherein n is>1, to homologues of lactic acid of formula CH.sub.n H.sub.2n+1 CHOHCOOH, wherein n is>1.
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