Method of treatment of inflamed tissues
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United States of America Patent
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Oct 18, 1994
Issued Date -
N/A
app pub date -
Oct 7, 1992
filing date -
Oct 20, 1989
priority date (Note) -
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Abstract
A method of and composition for concentrating a therapeutic agent in an inflamed dermal region are disclosed. The composition, which is also used in the method, is a liposomal composition. The liposomes contain the therapeutic agent in entrapped form and are composed of vesicle-forming lipids including a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer. After intravenous administration, the liposomes are taken up by the inflamed region within 24-48 hours, for site-specific release of entrapped compound into the inflamed region.
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