US Patent No: 5,358,514

Number of patents in Portfolio can not be more than 2000

Implantable microdevice with self-attaching electrodes

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Abstract

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An implantable microminiature stimulator and/or sensor (microdevice) is housed within a sealed housing that includes all the requisite electronic circuitry for inductively receiving power and control signals to sense of biopotential or other biomedical signals and/or to generate electrical stimulation pulse(s) between opposing electrodes. In a preferred embodiment, the housing of the microdevice is tubular, with opposing electrodes extending from each end. The electrodes are self-attaching electrodes that attach to a nerve or muscle without suturing. The electrodes are configured to helically curl around the desired nerve, thereby permitting the microdevice to stimulate the nerve or muscle, or sense signals associated with the nerve or muscle, using a minimal amount of energy. The electrodes and microdevice are sufficiently small to allow attachment to a single nerve, thereby preventing tethering of the nerve or muscle, and to allow their implantation within living tissue through small incisions or puncture holes. The muscle or nerve to which the microdevice is attached may be of any type, e.g., skeletal, smooth or cardiac.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHSANTA CLARITA, CA166

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Meadows, Paul Altadena, CA 6 1229
Schulman, Joseph H Santa Clarita, CA 159 20060
Strojnik, Primoz Granada Hills, CA 14 3510

Cited Art Landscape

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* Cited By Examiner

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Patent Info (Count) # Cites Year
 
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8,585,591 Method and system for providing basal profile modification in analyte monitoring and management systems 0 2010
8,993,331 Analyte monitoring system and methods for managing power and noise 0 2010
8,287,454 Analyte monitoring device and methods of use 2 2010
8,187,183 Continuous glucose monitoring system and methods of use 6 2010
8,765,059 Blood glucose tracking apparatus 0 2010
8,362,904 Analyte monitoring system and methods 0 2011
9,066,697 Analyte monitoring device and methods of use 0 2011
8,473,220 Method and device for early signal attenuation detection using blood glucose measurements 1 2012
9,095,290 Method and apparatus for providing rolling data in communication systems 0 2012
8,622,903 Continuous glucose monitoring system and methods of use 2 2012
8,652,043 Analyte monitoring device and methods of use 0 2012
8,593,287 Analyte monitoring system and methods 0 2012
8,597,575 Analyte monitoring devices and methods therefor 1 2012
8,920,319 Analyte monitoring device and methods of use 0 2012
9,035,767 Analyte monitoring system and methods 0 2013
9,177,456 Analyte monitoring system and methods 0 2013
9,078,607 Analyte monitoring device and methods of use 0 2013
9,020,573 Analyte monitoring device and methods of use 0 2013
8,676,513 Method and device for early signal attenuation detection using blood glucose measurements 0 2013
9,000,929 Analyte monitoring system and methods 1 2013
8,933,664 Method and system for powering an electronic device 0 2013
9,039,975 Analyte monitoring devices and methods therefor 0 2013
9,066,709 Method and device for early signal attenuation detection using blood glucose measurements 0 2014
8,915,850 Analyte monitoring device and methods of use 0 2014
 
MEDTRONIC MINIMED, INC. (7)
6,974,437 Microprocessor controlled ambulatory medical apparatus with hand held communication device 329 2001
6,733,446 Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods 424 2001
* 6,585,644 Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods 633 2001
6,950,708 Ambulatory medical apparatus and method using a telemetry system with predefined reception listening 384 2002
7,678,071 Microprocessor controlled ambulatory medical apparatus with hand held communication device 17 2003
7,831,310 Microprocessor controlled ambulatory medical apparatus with hand held communication device 57 2004
8,568,356 Ambulatory medical apparatus with hand held communication device 0 2011
 
Kenergy, Inc. (1)
* 7,749,265 Radio frequency antenna for a wireless intravascular medical device 0 2005
 
STIMEWAVE TECHNOLOGIES, INCORPORATED (1)
8,903,502 Methods and devices for modulating excitable tissue of the exiting spinal nerves 0 2013
 
MICRON DEVICES LLC (4)
9,199,089 Remote control of power or polarity selection for a neural stimulator 0 2012
8,849,412 Microwave field stimulator 0 2012
9,242,103 Relay module for implant 0 2012
9,220,897 Implantable lead 0 2013
 
CALIFORNIA INSTITUTE OF TECHNOLOGY (1)
* 2006/0280,655 Intravascular diagnostic and therapeutic sampling device 0 2006
 
SIMON FRASER UNIVERSITY (1)
* 5,487,756 Implantable cuff having improved closure 94 1994
 
CAMERON HEALTH, INC. (5)
9,144,683 Post-shock treatment in a subcutaneous device 0 2006
* 8,768,458 Unitary subcutaneous only implantable cardioverter-defibrillator 1 2012
8,706,217 Cardioverter-defibrillator having a focused shocking area and orientation thereof 2 2012
8,718,760 Subcutaneous implantable cardioverter-defibrillator placement methods 4 2013
9,138,589 Apparatus and method for identifying atrial arrhythmia by far-field sensing 0 2014
 
MEDTRONIC, INC. (24)
* 5,591,217 Implantable stimulator with replenishable, high value capacitive power source and method therefor 110 1995
* 5,782,891 Implantable ceramic enclosure for pacing, neurological, and other medical applications in the human body 176 1996
* 5,807,397 Implantable stimulator with replenishable, high value capacitive power source and method therefor 214 1996
* 5,769,877 High value capacitive, replenishable power source 209 1996
* 5,735,887 Closed-loop, RF-coupled implanted medical device 260 1996
* 6,099,495 Implantable electrical transducer powered from capacitive storage energy source 31 1998
7,013,178 Implantable medical device communication system 56 2002
7,742,818 Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof 12 2003
7,620,454 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 29 2003
* 2004/0236,382 Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof 65 2003
7,139,613 Implantable medical device communication system with pulsed power biasing 16 2003
7,286,884 Implantable lead including sensor 8 2004
8,265,770 Driver circuitry switchable between energy transfer and telemetry for an implantable medical device 5 2004
* 7,711,433 Switched power using telemetry in an implantable medical device 3 2005
* 2006/0020,307 Switched power using telemetry in an implantable medical device 16 2005
8,406,901 Sutureless implantable medical device fixation 0 2006
* 7,765,012 Implantable medical device including a conductive fixation element 0 2006
* 2008/0132,981 Implantable medical device including a conductive fixation element 9 2006
8,103,357 Implantable lead including sensor 0 2007
8,295,930 Medical device having resistance welded connections 0 2009
8,396,563 Clock synchronization in an implantable medical device system 3 2010
* 2012/0172,690 IMPLANTABLE MEDICAL DEVICE FIXATION 8 2011
9,220,906 Tethered implantable medical device deployment 0 2012
8,504,165 Clock synchronization in an implantable medical device system 0 2013
 
VITAL SENSORS HOLDING COMPANY (5)
7,686,768 Implantable pressure monitor 3 2006
7,682,313 Implantable pressure monitor 6 2006
* 2007/0118,039 Implantable device for telemetric measurement of blood pressure/temperature within the heart 24 2006
8,382,677 Anchored implantable pressure monitor 0 2011
8,376,953 Implantable pressure monitor 0 2011
 
Vital Sensors Holding Company, Inc. (2)
7,931,597 Anchored implantable pressure monitor 2 2010
7,931,598 Implantable pressure monitor 7 2010
 
UNIVERSITY OF ROCHESTER (4)
8,938,300 Leadless implantable intravascular electrophysiologic device for neurologic/cardiovascular sensing and stimulation 0 2005
8,849,416 Implantable bio-electro-physiologic interface matrix 0 2005
* 2008/0294,210 Leadless Implantable Cardioverter Defibrillator 2 2005
* 2008/0269,814 Implantable Bio-Electro-Physiologic Interface Matrix 0 2005
 
GUIDED DELIVERY SYSTEMS, INC. (13)
7,753,922 Devices and methods for cardiac annulus stabilization and treatment 26 2003
8,287,555 Devices and methods for heart valve repair 4 2003
9,226,825 Delivery devices and methods for heart valve repair 0 2004
7,758,637 Delivery devices and methods for heart valve repair 19 2004
7,666,193 Delivery devices and methods for heart valve repair 28 2004
7,883,538 Methods and devices for termination 17 2005
7,588,582 Methods for remodeling cardiac tissue 53 2005
8,066,766 Methods and devices for termination 18 2007
8,641,727 Devices and methods for heart valve repair 3 2008
7,922,762 Devices and methods for cardiac annulus stabilization and treatment 9 2008
9,072,513 Methods and devices for termination 0 2008
8,790,367 Multi-window guide tunnel 1 2009
8,795,298 Tether tensioning devices and related methods 0 2009
 
VARIAN MEDICAL SYSTEMS, INC. (2)
* 8,452,375 Systems and methods for locating and defining a target location within a human body 0 2003
* 2007/0265,491 Systems and methods for stabilizing a target location within a human body 17 2006
 
CODMAN NEURO SCIENCES SARL (2)
8,186,358 System and method for locating an internal device in a closed system 0 2005
8,929,996 Dual power supply switching circuitry for use in a closed system 0 2009
 
NERVONIX, INC. (4)
* 6,706,016 Nerve stimulator output control needle with depth determination capability and method of use 46 2001
7,047,085 Nerve stimulator output control needle with depth determination capability and method of use 1 2004
7,212,865 Nerve stimulator and method 46 2004
* 2005/0267,545 Nerve stimulator and method 5 2004
 
ADVANCED BIONICS, LLC (1)
8,027,735 Atraumatic high-retention headpiece 1 2009
 
CKM DIAGNOSTICS, INC. (1)
* 2004/0158,304 Nerve stimulator output control needle with depth determination capability and method of use 8 2004
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
* 2006/0052,836 Neurostimulation system 56 2005
 
WOLFE RESEARCH PTY LTD (1)
* 2006/0161,225 Medical implant system 81 2005
 
PENTAX CORPORATION (6)
7,001,329 Capsule endoscope guidance system, capsule endoscope holder, and capsule endoscope 25 2003
* 2004/0133,076 Capsule endoscope guidance system, capsule endoscope holder, and capsule endoscope 7 2003
7,109,933 Wearable jacket having communication function, and endoscope system employing wearable jacket 29 2005
* 2005/0195,785 Image signal processing device 1 2005
* 2005/0194,012 Wearable jacket for diagnosis and endoscope system employing wearable jacket 7 2005
* 2005/0195,118 Wearable jacket having communication function, and endoscope system employing wearable jacket 2 2005
 
C.R. BARD, INC. (9)
8,401,622 Biopsy marker with in situ-generated imaging properties 5 2007
* 2010/0010,341 Biopsy Marker with In Situ-Generated Imaging Properties 13 2007
8,670,818 Marker delivery device for tissue marker placement 1 2008
8,437,834 Breast marker 7 2011
9,042,965 Biopsy marker with in situ-generated imaging properties 0 2013
D716450 Tissue marker for intracorporeal site identification 0 2013
D716451 Tissue marker for intracorporeal site identification 0 2013
D715942 Tissue marker for intracorporeal site identification 0 2013
D715442 Tissue marker for intracorporeal site identification 0 2013
 
KIONIX, INC. (1)
6,324,430 Magnetic shield for primary coil of transcutaneous energy transfer device 50 1998
 
KLEIN, GEORGE J., M.D. (1)
8,078,279 Intravascular medical device 1 2009
 
CVRX, INC. (13)
8,086,314 Devices and methods for cardiovascular reflex control 12 2002
7,840,271 Stimulus regimens for cardiovascular reflex control 53 2005
8,290,595 Method and apparatus for stimulation of baroreceptors in pulmonary artery 6 2006
8,060,206 Baroreflex modulation to gradually decrease blood pressure 14 2006
7,813,812 Baroreflex stimulator with integrated pressure sensor 25 2006
8,838,246 Devices and methods for cardiovascular reflex treatments 0 2006
8,606,359 System and method for sustained baroreflex stimulation 2 2007
7,949,400 Devices and methods for cardiovascular reflex control via coupled electrodes 13 2009
8,583,236 Devices and methods for cardiovascular reflex control 0 2010
8,718,789 Electrode structures and methods for their use in cardiovascular reflex control 1 2010
9,044,609 Electrode structures and methods for their use in cardiovascular reflex control 0 2011
8,712,531 Automatic baroreflex modulation responsive to adverse event 1 2012
8,880,190 Electrode structures and methods for their use in cardiovascular reflex control 0 2012
 
THE JOHNS HOPKINS UNIVERSITY (1)
* 6,319,208 Telemetric in vivo bladder urine monitor system 46 1999
 
INVATEC S.P.A. (1)
8,612,022 Neuromodulation catheters and associated systems and methods 0 2012
 
BOSTON SCIENTIFIC SCIMED, INC. (6)
7,590,454 Modular stimulation lead network 14 2004
* 2005/0203,599 Modular stimulation lead network 73 2004
8,412,348 Intravascular self-anchoring integrated tubular electrode body 0 2004
* 2005/0251,238 Intravascular self-anchoring integrated tubular electrode body 30 2004
7,937,160 Methods for delivering cortical electrode leads into patient's head 3 2004
* 2006/0259,110 Collapsible/Expandable Tubular Electrode Leads 14 2006
 
BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (56)
* 6,061,596 Method for conditioning pelvic musculature using an implanted microstimulator 156 1998
6,735,474 Implantable stimulator system and method for treatment of incontinence and pain 280 2000
6,920,359 Deep brain stimulation system for the treatment of Parkinson's Disease or other disorders 95 2001
* 6,741,892 Movable contact locking mechanism for spinal cord stimulator lead connector 202 2001
7,054,689 Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction 39 2001
6,871,099 Fully implantable microstimulator for spinal cord stimulation as a therapy for chronic pain 169 2001
6,941,171 Implantable stimulator methods for treatment of incontinence and pain 125 2001
* 7,209,792 RF-energy modulation system through dynamic coil detuning 35 2002
* 7,054,692 Fixation device for implantable microdevices 87 2002
7,860,570 Implantable microstimulators and methods for unidirectional propagation of action potentials 94 2002
7,292,890 Vagus nerve stimulation via unidirectional propagation of action potentials 210 2002
7,203,548 Cavernous nerve stimulation via unidirectional propagation of action potentials 88 2002
* 2004/0015,205 Implantable microstimulators with programmable multielectrode configuration and uses thereof 201 2002
7,308,303 Thrombolysis and chronic anticoagulation therapy 22 2002
7,949,395 Implantable microdevice with extended lead and remote electrode 70 2003
* 2003/0114,905 Implantable microdevice with extended lead and remote electrode 156 2003
* 2004/0162,590 Fully implantable miniature neurostimulator for intercostal nerve stimulation as a therapy for angina pectoris 85 2003
7,539,542 Lead connector, lead adapter, and lead insertion apparatus 6 2003
* 2005/0055,064 Open loop deep brain stimulation system for the treatment of Parkinson's Disease or other disorders 5 2004
* 2005/0119,713 Methods for implanting a spinal cord stimulator 68 2004
7,840,279 Implantable microstimulator having a separate battery unit and methods of use thereof 4 2005
* 2006/0184,204 Implantable microstimulator having a separate battery unit and methods of use thereof 32 2005
* 7,627,383 Implantable stimulator 5 2005
* 2006/0212,087 Implantable stimulator 6 2005
7,660,631 Methods and systems for electrical and/or drug stimulation as a therapy for erectile dysfunction 7 2005
* 2005/0209,652 Methods and systems for electrical and/or drug stimulation as a therapy for erectile dysfunction 31 2005
7,801,600 Controlling charge flow in the electrical stimulation of tissue 7 2005
8,175,717 Ultracapacitor powered implantable pulse generator with dedicated power supply 11 2005
* 2007/0055,308 Ultracapacitor powered implantable pulse generator with dedicated power supply 36 2005
7,729,758 Magnetically coupled microstimulators 17 2005
7,890,177 Device and therapy for erectile dysfunction and other sexual dysfunction 1 2006
7,865,243 Device and therapy for erectile dysfunction and other sexual dysfunction 2 2006
8,214,048 Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction 1 2006
7,801,602 Controlling stimulation parameters of implanted tissue stimulators 7 2006
8,019,441 Collapsible/expandable tubular electrode leads 0 2006
7,899,539 Cavernous nerve stimulation via unidirectional propagation of action potentials 13 2006
* 2007/0021,800 CAVERNOUS NERVE STIMULATION VIA UNIDIRECTIONAL PROPAGATION OF ACTION POTENTIALS 25 2006
7,877,136 Enhancement of neural signal transmission through damaged neural tissue via hyperpolarizing electrical stimulation current 45 2007
9,248,280 Closed-loop feedback for steering stimulation energy within tissue 0 2007
* 2009/0118,787 Closed-loop feedback for steering stimulation energy within tissue 18 2007
* 2009/0118,804 METHOD OF MOUNTING MINIMALLY INVASIVE PLUG ELECTRODES WITHIN CRANIUM OF PATIENT 7 2007
7,783,362 Vagus nerve stimulation via unidirectional propagation of action potentials 5 2007
7,877,137 Thrombolysis and chronic anticoagulation therapy 0 2007
* 2008/0286,327 THOMBOLYSIS AND CHRONIC ANTICOAGULATION THERAPY 0 2007
8,355,786 Lead connector, lead adapter, and lead insertion apparatus 1 2009
* 2009/0228,087 LEAD CONNECTOR, LEAD ADAPTER, AND LEAD INSERTION APPARATUS 1 2009
8,185,208 Modular stimulation lead network 1 2009
8,060,215 Implantable microstimulator having a battery unit and methods of use therefor 0 2010
* 2010/0280,572 OPEN LOOP DEEP BRAIN STIMULATION SYSTEM FOR THE TREATMENT OF PARKINSON'S DISEASE OR OTHER DISORDERS 1 2010
8,548,604 Implantable microstimulators and methods for unidirectional propagation of action potentials 0 2010
* 8,655,451 Telemetry system for use with microstimulator 0 2011
* 2011/0137,378 Telemetry System for Use With Microstimulator 2 2011
8,712,547 Cavernous nerve stimulation via unidirectional propagation of action potentials 0 2011
8,032,220 Method of implanting microdevice with extended lead and remote electrode 0 2011
8,588,917 Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction 5 2012
9,079,041 Systems and methods for communicating with an implantable stimulator 0 2013
 
Navotek Medical Ltd. (1)
8,164,064 Localization of a radioactive source within a body of a subject 0 2010
 
SENORX, INC. (18)
* 2008/0294,039 Assembly with hemostatic and radiographically detectable pellets 17 2008
* 8,718,745 Tissue site markers for in vivo imaging 1 2010
* 2010/0298,698 TISSUE SITE MARKERS FOR IN VIVO IMAGING 9 2010
8,447,386 Marker or filler forming fluid 0 2010
* 2011/0092,815 MARKER OR FILLER FORMING FLUID 7 2010
8,361,082 Marker delivery device with releasable plug 10 2011
8,498,693 Intracorporeal marker and marker delivery device 0 2011
8,626,269 Fibrous marker and intracorporeal delivery thereof 8 2011
9,149,341 Deployment of polysaccharide markers for treating a site within a patient 0 2011
8,668,737 Tissue marking implant 2 2012
8,784,433 Plugged tip delivery tube for marker placement 0 2012
8,626,270 Cavity-filling biopsy site markers 9 2012
9,044,162 Marker delivery device with releasable plug 0 2013
8,639,315 Marker or filler forming fluid 7 2013
8,880,154 Fibrous marker and intracorporeal delivery thereof 0 2013
8,965,486 Cavity filling biopsy site markers 0 2013
9,039,763 Tissue marking implant 1 2014
9,237,937 Cavity-filling biopsy site markers 0 2015
* Cited By Examiner