US Patent No: 5,358,514

Number of patents in Portfolio can not be more than 2000

Implantable microdevice with self-attaching electrodes

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Abstract

An implantable microminiature stimulator and/or sensor (microdevice) is housed within a sealed housing that includes all the requisite electronic circuitry for inductively receiving power and control signals to sense of biopotential or other biomedical signals and/or to generate electrical stimulation pulse(s) between opposing electrodes. In a preferred embodiment, the housing of the microdevice is tubular, with opposing electrodes extending from each end. The electrodes are self-attaching electrodes that attach to a nerve or muscle without suturing. The electrodes are configured to helically curl around the desired nerve, thereby permitting the microdevice to stimulate the nerve or muscle, or sense signals associated with the nerve or muscle, using a minimal amount of energy. The electrodes and microdevice are sufficiently small to allow attachment to a single nerve, thereby preventing tethering of the nerve or muscle, and to allow their implantation within living tissue through small incisions or puncture holes. The muscle or nerve to which the microdevice is attached may be of any type, e.g., skeletal, smooth or cardiac.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHSANTA CLARITA, CA183

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Meadows, Paul La Canada, CA 5 590
Schulman, Joseph H Santa Clarita, CA 182 10977
Strojnik, Primoz Granada Hills, CA 14 2171

Cited Art

Patent Info (Count) # Cites Year
 
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CASE WESTERN RESERVE UNIVERSITY (1)
4,602,624 Implantable cuff, method of manufacture, and method of installation 110 1984
 
GREATBATCH LTD. (1)
2005/0190,527 SPRING CONTACT SYSTEM FOR EMI FILTERED HERMETIC SEALS FOR ACTIVE IMPLANTABLE MEDICAL DEVICES 2005
 
HAMEDI, HASSAN (1)
4,934,368 Multi-electrode neurological stimulation apparatus 52 1988
 
HILDEBRANDT (1)
4,524,774 Apparatus and method for the stimulation of a human muscle 56 1982
 
HUNTINGTON INSTITUTE OF APPLIED RESEARCH (1)
4,573,481 Implantable electrode array 264 1984
 
HUNTINGTON MEDICAL RESEARCH INSTITUTES (1)
4,920,979 Bidirectional helical electrode for nerve stimulation 103 1988
 
KESTER; BEATRICE T. (1)
4,763,656 Transcutaneous electrical nerve stimulation device and method 21 1987
 
STODDARD, HANNIS L. III (1)
4,333,072 Identification device 155 1979
 
TELECTRONICS, INC., A DE CORP. (1)
4,198,991 Cardiac pacer lead 35 1978
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
4,679,560 Wide band inductive transdermal power and data link 60 1985

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (34)
6,061,596 Method for conditioning pelvic musculature using an implanted microstimulator 99 1998
6,735,474 Implantable stimulator system and method for treatment of incontinence and pain 150 2000
6,920,359 Deep brain stimulation system for the treatment of Parkinson's Disease or other disorders 49 2001
6,741,892 Movable contact locking mechanism for spinal cord stimulator lead connector 80 2001
7,054,689 Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction 17 2001
6,871,099 Fully implantable microstimulator for spinal cord stimulation as a therapy for chronic pain 62 2001
6,941,171 Implantable stimulator methods for treatment of incontinence and pain 63 2001
7,209,792 RF-energy modulation system through dynamic coil detuning 6 2002
7,054,692 Fixation device for implantable microdevices 45 2002
7,860,570 Implantable microstimulators and methods for unidirectional propagation of action potentials 14 2002
7,292,890 Vagus nerve stimulation via unidirectional propagation of action potentials 72 2002
7,203,548 Cavernous nerve stimulation via unidirectional propagation of action potentials 43 2002
7,308,303 Thrombolysis and chronic anticoagulation therapy 16 2002
7,949,395 Implantable microdevice with extended lead and remote electrode 1 2003
7,539,542 Lead connector, lead adapter, and lead insertion apparatus 1 2003
7,840,279 Implantable microstimulator having a separate battery unit and methods of use thereof 1 2005
7,627,383 Implantable stimulator 3 2005
7,660,631 Methods and systems for electrical and/or drug stimulation as a therapy for erectile dysfunction 1 2005
7,801,600 Controlling charge flow in the electrical stimulation of tissue 2 2005
8,175,717 Ultracapacitor powered implantable pulse generator with dedicated power supply 0 2005
7,729,758 Magnetically coupled microstimulators 2 2005
7,890,177 Device and therapy for erectile dysfunction and other sexual dysfunction 0 2006
7,865,243 Device and therapy for erectile dysfunction and other sexual dysfunction 0 2006
8,214,048 Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction 0 2006
7,801,602 Controlling stimulation parameters of implanted tissue stimulators 2 2006
8,019,441 Collapsible/expandable tubular electrode leads 0 2006
7,899,539 Cavernous nerve stimulation via unidirectional propagation of action potentials 3 2006
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7,783,362 Vagus nerve stimulation via unidirectional propagation of action potentials 0 2007
7,877,137 Thrombolysis and chronic anticoagulation therapy 0 2007
8,355,786 Lead connector, lead adapter, and lead insertion apparatus 0 2009
8,185,208 Modular stimulation lead network 0 2009
8,060,215 Implantable microstimulator having a battery unit and methods of use therefor 0 2010
8,032,220 Method of implanting microdevice with extended lead and remote electrode 0 2011
 
ABBOTT DIABETES CARE INC. (27)
7,811,231 Continuous glucose monitoring system and methods of use 14 2003
8,066,639 Glucose measuring device for use in personal area network 0 2004
8,112,240 Method and apparatus for providing leak detection in data monitoring and management systems 0 2005
7,976,778 Blood glucose tracking apparatus 2 2005
7,766,829 Method and system for providing basal profile modification in analyte monitoring and management systems 3 2005
8,226,891 Analyte monitoring devices and methods therefor 1 2006
7,620,438 Method and system for powering an electronic device 0 2006
8,123,686 Method and apparatus for providing rolling data in communication systems 0 2007
8,231,532 Analyte monitoring device and methods of use 0 2007
7,920,907 Analyte monitoring system and method 3 2007
7,928,850 Analyte monitoring system and methods 11 2008
8,103,456 Method and device for early signal attenuation detection using blood glucose measurements 2 2009
8,255,031 Analyte monitoring device and methods of use 0 2009
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8,235,896 Analyte monitoring device and methods of use 0 2009
8,177,716 Analyte monitoring device and methods of use 0 2009
8,268,243 Blood glucose tracking apparatus and methods 0 2009
8,226,557 Analyte monitoring device and methods of use 0 2009
8,236,242 Blood glucose tracking apparatus and methods 0 2010
8,287,454 Analyte monitoring device and methods of use 0 2010
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8,362,904 Analyte monitoring system and methods 0 2011
 
MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L. (20)
7,162,303 Renal nerve stimulation method and apparatus for treatment of patients 52 2003
6,978,174 Methods and devices for renal nerve blocking 49 2004
7,653,438 Methods and apparatus for renal neuromodulation 11 2005
8,150,518 Renal nerve stimulation method and apparatus for treatment of patients 0 2005
7,647,115 Renal nerve stimulation method and apparatus for treatment of patients 11 2005
8,145,316 Methods and apparatus for renal neuromodulation 0 2005
7,937,143 Methods and apparatus for inducing controlled renal neuromodulation 2 2005
7,620,451 Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach 15 2006
8,175,711 Methods for treating a condition or disease associated with cardio-renal function 1 2006
8,150,519 Methods and apparatus for bilateral renal neuromodulation 2 2006
8,150,520 Methods for catheter-based renal denervation 3 2006
8,145,317 Methods for renal neuromodulation 2 2006
8,131,371 Methods and apparatus for monopolar renal neuromodulation 1 2006
7,853,333 Methods and apparatus for multi-vessel renal neuromodulation 4 2006
7,617,005 Methods and apparatus for thermally-induced renal neuromodulation 17 2006
8,347,891 Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen 0 2006
8,131,372 Renal nerve stimulation method for treatment of patients 1 2007
7,717,948 Methods and apparatus for thermally-induced renal neuromodulation 14 2007
8,433,423 Methods for multi-vessel renal neuromodulation 0 2010
8,398,630 Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen 0 2012
 
E. HELLER & COMPANY (18)
8,409,131 Analyte monitoring device and methods of use 0 2007
7,860,544 Analyte monitoring device and methods of use 4 2007
8,260,392 Analyte monitoring device and methods of use 0 2008
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8,306,598 Analyte monitoring device and methods of use 0 2009
8,275,439 Analyte monitoring device and methods of use 0 2009
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8,372,005 Analyte monitoring device and methods of use 0 2009
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8,353,829 Analyte monitoring device and methods of use 0 2009
7,885,699 Analyte monitoring device and methods of use 3 2010
7,869,853 Analyte monitoring device and methods of use 3 2010
8,226,558 Analyte monitoring device and methods of use 0 2010
 
MEDTRONIC, INC. (18)
5,591,217 Implantable stimulator with replenishable, high value capacitive power source and method therefor 64 1995
5,782,891 Implantable ceramic enclosure for pacing, neurological, and other medical applications in the human body 105 1996
5,807,397 Implantable stimulator with replenishable, high value capacitive power source and method therefor 147 1996
5,769,877 High value capacitive, replenishable power source 120 1996
5,735,887 Closed-loop, RF-coupled implanted medical device 152 1996
6,099,495 Implantable electrical transducer powered from capacitive storage energy source 18 1998
7,013,178 Implantable medical device communication system 38 2002
7,742,818 Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof 1 2003
7,620,454 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 5 2003
7,139,613 Implantable medical device communication system with pulsed power biasing 4 2003
7,286,884 Implantable lead including sensor 5 2004
8,265,770 Driver circuitry switchable between energy transfer and telemetry for an implantable medical device 0 2004
7,711,433 Switched power using telemetry in an implantable medical device 1 2005
8,406,901 Sutureless implantable medical device fixation 0 2006
7,765,012 Implantable medical device including a conductive fixation element 0 2006
8,103,357 Implantable lead including sensor 0 2007
8,295,930 Medical device having resistance welded connections 0 2009
8,396,563 Clock synchronization in an implantable medical device system 0 2010
 
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (16)
5,999,848 Daisy chainable sensors and stimulators for implantation in living tissue 275 1997
6,185,452 Battery-powered patient implantable device 333 1998
6,947,782 Miniature implantable connectors 3 2001
6,738,672 Miniature implantable connectors 13 2001
6,695,885 Method and apparatus for coupling an implantable stimulator/sensor to a prosthetic device 56 2001
7,107,103 Full-body charger for battery-powered patient implantable device 18 2002
7,079,881 Substrate sensor 5 2002
7,450,998 Method of placing an implantable device proximate to neural/muscular tissue 1 2003
7,114,502 Battery-powered patient implantable device 54 2003
7,235,050 Implantable device for processing neurological signals 4 2004
7,460,911 System and method suitable for treatment of a patient with a neurological deficit by sequentially stimulating neural pathways using a system of discrete implantable medical devices 1 2004
7,245,972 Electrical treatment to treat shoulder subluxation 0 2005
7,513,257 System of implantable devices for monitoring and/or affecting body parameters 4 2005
7,555,328 Implantable substrate sensor with back-to-back electrodes 2 2006
8,301,266 Structure for placement of an implantable device 0 2008
8,155,745 System and method for gait rehabilitation 0 2008
 
ADVANCED NEUROMODULATION SYSTEMS, INC. (11)
7,756,584 Methods and apparatus for effectuating a lasting change in a neural-function of a patient 0 2002
7,831,305 Neural stimulation system and method responsive to collateral neural activity 3 2002
7,565,199 Methods for treating and/or collecting information regarding neurological disorders, including language disorders 0 2003
7,684,866 Apparatus and methods for applying neural stimulation to a patient 6 2004
7,565,200 Systems and methods for selecting stimulation sites and applying treatment, including treatment of symptoms of Parkinson's disease, other movement disorders, and/or drug side effects 0 2004
7,483,747 Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy 9 2005
7,983,762 Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy 0 2008
8,121,695 Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures 1 2009
8,073,546 Methods and apparatus for effectuating a lasting change in a neural-function of a patient 0 2010
8,433,414 Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures 0 2012
8,412,335 Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators 0 2012
 
GUIDED DELIVERY SYSTEMS INC. (8)
7,753,922 Devices and methods for cardiac annulus stabilization and treatment 8 2003
8,287,555 Devices and methods for heart valve repair 0 2003
7,758,637 Delivery devices and methods for heart valve repair 9 2004
7,666,193 Delivery devices and methods for heart valve repair 10 2004
7,883,538 Methods and devices for termination 6 2005
7,588,582 Methods for remodeling cardiac tissue 18 2005
8,066,766 Methods and devices for termination 3 2007
7,922,762 Devices and methods for cardiac annulus stabilization and treatment 5 2008
 
SYNECOR, LLC (7)
8,239,045 Device and method for retaining a medical device within a vessel 0 2003
7,529,589 Intravascular electrophysiological system and methods 9 2004
7,617,007 Method and apparatus for retaining medical implants within body vessels 2 2004
7,747,335 Implantable medical device having pre-implant exoskeleton 2 2004
7,734,343 Implantable intravascular device for defibrillation and/or pacing 1 2006
7,899,554 Intravascular System and Method 0 2007
7,840,282 Method and apparatus for retaining medical implants within body vessels 1 2009
 
CVRX, INC. (6)
8,086,314 Devices and methods for cardiovascular reflex control 1 2002
7,840,271 Stimulus regimens for cardiovascular reflex control 20 2005
8,290,595 Method and apparatus for stimulation of baroreceptors in pulmonary artery 0 2006
8,060,206 Baroreflex modulation to gradually decrease blood pressure 1 2006
7,813,812 Baroreflex stimulator with integrated pressure sensor 1 2006
7,949,400 Devices and methods for cardiovascular reflex control via coupled electrodes 1 2009
 
MEDTRONIC MINIMED, INC. (6)
6,974,437 Microprocessor controlled ambulatory medical apparatus with hand held communication device 149 2001
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6,950,708 Ambulatory medical apparatus and method using a telemetry system with predefined reception listening 180 2002
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THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (6)
8,082,039 Stimulation systems 1 2005
7,580,753 Method and system for stimulating a dorsal root ganglion 12 2005
7,502,651 Methods for stimulating a dorsal root ganglion 4 2005
7,450,993 Methods for selective stimulation of a ganglion 5 2005
7,447,546 Methods of neurostimulating targeted neural tissue 8 2005
8,229,565 Methods for stimulating a dorsal root ganglion 0 2009
 
NANOSTIM, INC. (5)
8,352,025 Leadless cardiac pacemaker triggered by conductive communication 0 2006
8,010,209 Delivery system for implantable biostimulator 0 2006
7,945,333 Programmer for biostimulator system 1 2006
7,937,148 Rate responsive leadless cardiac pacemaker 1 2006
8,295,939 Programmer for biostimulator system 0 2011
 
PMD HOLDINGS CORPORATION, A CORPORATION OF ILLINOIS (4)
6,206,835 Remotely interrogated diagnostic implant device with electrically passive sensor 105 1999
6,170,488 Acoustic-based remotely interrogated diagnostic implant device and system 103 1999
6,092,530 Remotely interrogated implant device with sensor for detecting accretion of biological matter 32 1999
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VITAL SENSORS HOLDING COMPANY (4)
7,686,768 Implantable pressure monitor 3 2006
7,682,313 Implantable pressure monitor 3 2006
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8,376,953 Implantable pressure monitor 0 2011
 
ABIOMED, INC. (3)
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6,324,431 Transcutaneous energy transfer device with magnetic field protected components in secondary coil 29 1999
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ADVANCED BIONICS, LLC (3)
7,450,994 Estimating flap thickness for cochlear implants 10 2004
7,920,924 Estimating flap thickness for cochlear implants 0 2008
8,027,735 Atraumatic high-retention headpiece 1 2009
 
AMS RESEARCH CORPORATION (3)
8,195,296 Apparatus for treating stress and urge incontinence 0 2006
8,160,710 Systems and methods for implanting tissue stimulation electrodes in the pelvic region 0 2007
8,380,312 Multi-zone stimulation implant system and method 0 2010
 
BOSTON SCIENTIFIC SCIMED, INC. (3)
7,590,454 Modular stimulation lead network 5 2004
8,412,348 Intravascular self-anchoring integrated tubular electrode body 0 2004
7,937,160 Methods for delivering cortical electrode leads into patient's head 1 2004
 
NERVONIX, INC. (3)
6,706,016 Nerve stimulator output control needle with depth determination capability and method of use 26 2001
7,047,085 Nerve stimulator output control needle with depth determination capability and method of use 1 2004
7,212,865 Nerve stimulator and method 13 2004
 
C.R. BARD, INC. (2)
8,401,622 Biopsy marker with in situ-generated imaging properties 0 2007
8,437,834 Breast marker 0 2011
 
MOTEDATA INC. (2)
7,388,488 Method and system for storing, retrieving, and managing data for tags 0 2004
7,956,742 Method and system for storing, retrieving, and managing data for tags 0 2007
 
NEUROSTREAM TECHNOLOGIES GENERAL PARTNERSHIP (2)
6,996,435 Implantable signal amplifying circuit for electroneurographic recording 1 2001
8,086,305 Implantable signal amplifying circuit for electroneurographic recording 0 2005
 
NEUROSYSTEC CORPORATION (2)
7,803,148 Flow-induced delivery from a drug mass 1 2007
8,298,176 Flow-induced delivery from a drug mass 0 2010
 
PENTAX CORPORATION (2)
7,001,329 Capsule endoscope guidance system, capsule endoscope holder, and capsule endoscope 16 2003
7,109,933 Wearable jacket having communication function, and endoscope system employing wearable jacket 23 2005
 
THORATEC CORPORATION (2)
6,149,683 Power system for an implantable heart pump 15 1998
6,592,620 Power system for an implantable heart pump 2 2000
 
VITAL SENSORS HOLDING COMPANY, INC. (2)
7,931,597 Anchored implantable pressure monitor 2 2010
7,931,598 Implantable pressure monitor 4 2010
 
ARGENTUMCIDALELECTRICS, INC. (1)
8,135,466 Prophylactic bactericidal implant 0 2006
 
COCHLEAR LIMITED (1)
7,822,479 Connector for implantable hearing aid 0 2008
 
CODMAN NEURO SCIENCES SARL (1)
8,186,358 System and method for locating an internal device in a closed system 0 2005
 
ETHICON, INC. (1)
8,352,026 Implantable pulse generators and methods for selective nerve stimulation 0 2007
 
KENERGY, INC. (1)
7,749,265 Radio frequency antenna for a wireless intravascular medical device 0 2005
 
KIONIX, INC. (1)
6,324,430 Magnetic shield for primary coil of transcutaneous energy transfer device 36 1998
 
KLEIN, GEORGE J., M.D. (1)
8,078,279 Intravascular medical device 0 2009
 
NANTONG UNIVERSITY (1)
8,000,806 Neural channel bridge aided by a micro-electronic system 0 2006
 
NAVOTEK MEDICAL LTD. (1)
8,164,064 Localization of a radioactive source within a body of a subject 0 2010
 
NEURODAN A /S (1)
6,366,815 Implantable nerve stimulator electrode 36 1999
 
OTOLOGICS LLP (1)
6,517,476 Connector for implantable hearing aid 28 2000
 
PACESETTER, INC. (1)
7,294,108 Cardiac event microrecorder and method for implanting same 3 2005
 
SEATTLE SYSTEMS, INC. (1)
6,500,210 System and method for providing a sense of feel in a prosthetic or sensory impaired limb 35 1996
 
SENORX, INC. (1)
8,361,082 Marker delivery device with releasable plug 0 2011
 
SIMON FRASER UNIVERSITY (1)
5,487,756 Implantable cuff having improved closure 43 1994
 
SPINAL MODULATION, INC. (1)
8,380,318 Pain management with stimulation subthreshold to paresthesia 0 2010
 
SULZER INTERMEDICS INC. (1)
5,701,895 Subcutaneous electrical data port 20 1996
 
THE JOHNS HOPKINS UNIVERSITY (1)
6,319,208 Telemetric in vivo bladder urine monitor system 33 1999
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (5)
6,297,727 Transponder identification and record assembly 77 1997
6,109,529 Bar code identification and record assembly 5 1997
6,197,434 Glazing covered ferrite core electrode terminal of a surface mounting inductor 1 2000
8,447,386 Marker or filler forming fluid 0 2010
8,444,640 Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen 0 2012