Device for moving a target-bearing solid through a liquid for detection while being contained
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United States of America Patent
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Nov 15, 1994
Grant Date -
N/A
app pub date -
Jun 1, 1992
filing date -
Jun 1, 1992
priority date (Note) -
In Force
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Abstract
There are described a device and method for doing confined reactions such as PCR amplification and detection, wherein solids (e.g., beads) used to obtain separation between bound and 'free' label reagents, are transferred from region to region, specifically through a wash liquid so as to wash off the 'free' label reagent from the solids. Separate chambers have dividers that are overcome by piercing or by liquification, to create passageways for the transfer of the solids. The passageways remain contained within the device.
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