Polychelants containing macrocyclic chelant moieties
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United States of America Patent
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Nov 15, 1994
Issued Date -
N/A
app pub date -
Jan 16, 1990
filing date -
Apr 7, 1989
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Abstract
There are provided polychelants and their metal chelates which are useful in diagnostic imaging and in radiotherapy and which comprise a plurality of macrocyclic chelant moieties, e.g, DOTA residues, conjugated to a polyamine backbone molecule, e.g, polylysine. To produce a site-specific polychelate, one or more of the macrocyclic chelant carrying backbone molecules may be conjugated to a site-directed macromolecule, e.g. a protein.
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