Processes of preparing sialoglycosyl compounds
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United States of America Patent
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Dec 6, 1994
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N/A
app pub date -
Feb 12, 1992
filing date -
Feb 28, 1991
priority date (Note) -
Expired
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Abstract
An improved process for the preparation of O-glycosyl compounds of sialic acid, which are useful as intermediates in the synthesis of sialoconjugated glycosides. This process comprises effecting condensation reaction between thioglycosides of sialic acid and sugar derivatives in the presence of N-iodosuccinimide and trifluoromethanesulfonic acid. O-glycosyl compounds of sialic acid are prepared in high resio- and stereo-selectivity and in high yields.
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