Method of manufacturing pliable biological grafts materials
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United States of America Patent
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Dec 27, 1994
Issued Date -
N/A
app pub date -
Jun 9, 1993
filing date -
Feb 14, 1991
priority date (Note) -
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Abstract
Preparing chemically cross-linked collagenous biological graft material by preparation processes which include the step of altering the locations and/or orientations of chemical cross-linkages formed during the collagen cross-linking process. Embodiments of the method include various processes whereby physical force, stress or movement is applied to alter the relative positioning of the collagen fibers within the graft materials during at least the initial period of exposure to the collagen cross-linking reagent.
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