Recombinant erythropoietin receptor protein
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United States of America Patent
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Jan 3, 1995
Issued Date -
N/A
app pub date -
Jun 10, 1993
filing date -
Feb 3, 1989
priority date (Note) -
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Abstract
The invention described encompasses an isolated DNA sequence encoding all or a portion thereof of a cell surface receptor murine and human erythropoietin (hereinafter EPO-R), along with the isolated polypeptide expressed by the DNA sequence (i.e., isolated EPO-R). The invention also encompasses host cells containing the above-described DNA sequence, preferably, host cells which express the polypeptide encoded by the DNA sequence (EPO-R) at a significantly higher level than that produced by normal red blood cell precursors. The invention further encompasses DNA sequences encoding secreted forms of the human EPO-R and polypeptides corresponding thereto. The EPO-receptor in all of the disclosed forms can be used as models for designing drugs or in pharmaceutical compositions for treating anemias.
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Patent Owner(s)
| Patent Owner | Address | |
|---|---|---|
| GENETICS INSTITUTE INC | MASSACHUSETTS MASSACHUSETTS |
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Inventor(s)
| Inventor Name | Address | # of filed Patents | Total Citations |
|---|---|---|---|
| D'Andrea, Alan | Winchester, MA | 15 | 111 |
| Jones, Simon S | Somerville, MA | 10 | 242 |
| Wong, Gordon G | Brookline, MA | 53 | 1856 |
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| Fee | Large entity fee | small entity fee | micro entity fee |
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| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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