Generalized method for assessment of colorectal carcinoma
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United States of America Patent
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Jan 10, 1995
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N/A
app pub date -
Mar 16, 1989
filing date -
Mar 16, 1989
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Abstract
A method is provided for assessing the generalized genetic change which occurs during tumorigenesis. The method relies on measurement of loss of a large number of alleles from the chromosomes of the tumor cells. The alleles are RFLP markers. The role of any of the particular alleles in tumorigenesis need not be known. The amount of allelic loss allows a prognosis to be made regarding tumor metastasis, tumor recurrence, and mortality.
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