Methods of diagnosing pre-cancer or cancer states using probes for detecting mutant p53

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United States of America Patent

PATENT NO 5382510
SERIAL NO

07912011

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Abstract

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A panel of probes that detect and distinguish between sets of human p53 gene or protein mutations that frequently occur or are selected for in pre-cancer and cancer cells, each set giving rise to a phenotype that is different from that of wild-type p53 and of at least one other set of p53 mutants.

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Patent Owner(s)

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THE TRUSTEES OF PRINCETON UNIVERSITYPRINCETON NJ 08544

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Finlay, Cathy A Yardley, PA 4 82
Levine, Arnold J Princeton, NJ 22 422
Shenk, Thomas E Princeton, NJ 15 589

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