Pharmaceutical formulations comprising microcapsules
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United States of America Patent
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-
Jan 24, 1995
Issued Date -
N/A
app pub date -
Jun 29, 1993
filing date -
Aug 11, 1986
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Pharmaceutical formulations comprise (i) microcapsules which consist essentially of a biocompatible polymeric wall material encapsulating a drug, and (ii) a lipid soluble surfactant which is mixed with the microcapsules or is incorporated within or coats the wall material of the microcapsules. Such formulations may be presented as an aerosol or dry powder for inhalation. Microcapsules with surfactant incorporated in the wall material may be suspended in a pharmaceutically acceptable water-immiscible oil and the resulting suspension emulsified in an aqueous medium to obtain a formulation for oral administration.
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