Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases
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United States of America
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Jan 24, 1995
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Feb 21, 1992
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Feb 21, 1992
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Abstract
Compounds of the formula ##STR1## and pharmaceutical compositions comprising them, wherein R.sup.1, R.sup.2, R.sup.3, W, X and Z are as defined below. The compounds are inhibitors of 5-lipoxygenase enzyme and antagonists of leukotriene B4, leukotriene C4, leukotriene D4 and leukotriene E4.
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