Pharmaceutically active 1,2,4-triamino-benzene derivatives, processes for their preparation and pharmaceutical compositions containing them
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United States of America Patent
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Jan 24, 1995
Grant Date -
N/A
app pub date -
Jan 8, 1993
filing date -
Jan 8, 1992
priority date (Note) -
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Abstract
Pharmacologically active 1,2,4-triaminobenzene derivatives of the General Formula I: ##STR1## where the symbols R1' R2' R3' R4' R5' Ar and Alk have the following meanings: where the symbols R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, Ar and Alk have the following meanings: R.sub.1 : hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkanoyl or the radical Ar; R.sub.2 : hydrogen or C.sub.1 -C.sub.6 -alkyl; R.sub.3 : C.sub.1 -C.sub.6 -alkoxy, NH.sub.2, C.sub.1 -C.sub.6 -alkylamino, C.sub.1 -C.sub.6 -dialkylamino, amino substituted by the radical Ar, C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.2 -C.sub.6 -alkynyl, the radical Ar or the radical ArO--; R.sub.4 : hydrogen, C.sub.1 -C.sub.6 -alkyl or the radical Ar; R.sub.5 : hydrogen or C.sub.1 -C.sub.6 -alkyl or the radical Ar; Alk: a straight or branched alkylene group containing 1-9 carbon atoms, which can also be substituted by the radical Ar.
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