Formulations for delivery of osteogenic proteins

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United States of America Patent

PATENT NO 5385887
SERIAL NO

08119772

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Abstract

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A composition is disclosed comprising a pharmaceutically acceptable admixture of an osteogenic protein; a porous particulate polymer matrix; an osteogenic protein-sequestering amount of blood clot; and a calcium sulfate hemihydrate-containing substance. Also disclosed are formulations of bone morphogenetic proteins with improved solubility and/or stability characteristics.

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Patent Owner(s)

Patent OwnerAddress
GENETICS INSTITUTE LLC87 CAMBRIDGE PARK DRIVE CAMBRIDGE MASSACHUSETTS 02140 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huberty, Michael C Andover, MA 1 257
Northey, Jr Richard P Ipswich, MA 1 257
Schrier, Jay A Andover, MA 2 264
Yim, Kalvin W K N. andover, MA 1 257

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