Method for enhancing delivery of chemotherapy employing high-frequency force fields
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United States of America Patent
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Feb 7, 1995
Grant Date -
N/A
app pub date -
Feb 1, 1993
filing date -
Feb 1, 1993
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Abstract
Pulse shocks of high-frequency wave energy (e.g. RF, microwave, high-energy infra-red or laser electromagnetic wave energy or ultrasonic acoustic wave energy), rather than DC electric pulses, are employed to non-invasively produce force fields of an intensity sufficient to create transient pores in the plasma membranes of targeted cells, such as tumor cells or other diseased cells, through which either locally or systemically applied drug or chemotherapeutic agents can easily enter and be taken up by the targeted cells, even for (1) the cells of a deep-seated tumor, (2) non-localized metastasized tumor cells within a patient's body, or (3) cells (e.g., blood cells) temporarily removed to outside of a patient's body.
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