Method for performing a solid-phase extraction under pressurized conditions

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United States of America Patent

SERIAL NO

08027080

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Abstract

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A method of performing a solid phase extraction on an aqueous fluid using a hydrophobic, solid-phase extraction medium (40), which method comprises: (a) placing (10) a hydrophobic, solid-phase extraction medium (40) inside of a pressurizable housing (18) having an inlet (25) and an outlet (32), the hydrophobic, solid-phase extraction medium (40) being positioned in the pressurizable housing (18) such that a liquid moving from the inlet (25) to the outlet (32) passes through the solid-phase extraction medium (40); (b) priming (12) the hydrophobic, solid-phase extraction medium (40) with a water-miscible organic liquid by passing the water-miscible organic liquid from the inlet (25) to the outlet (32) under positive pressure; and (c) passing (14) an aqueous liquid from the inlet (25) to the outlet (32) under positive pressure; wherein the water-miscible organic liquid and aqueous liquid are passed from the inlet (25) to the outlet (32) such that the solid-phase extraction medium (40) is completely and continuously immersed in liquid in the pressurizable housing (18) during steps (b) and (c).

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Patent Owner(s)

  • MINNESOTA MINING AND MANUFACTURING COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aysta, James E Stillwater, MN 33 1084
Pieper, Richard M St. Paul, MN 3 60

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