Benzimidazolinones substituted with phenoxyphenylacetic acid derivatives
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United States of America Patent
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Feb 21, 1995
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N/A
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Jul 20, 1993
filing date -
Jul 20, 1993
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Abstract
Phenoxyphenylacetic acids and derivatives of the general structural formula I ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, inflammatory diseases including Raynaud's disease and asthma.
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