Sustained release formulations for 24 hour release of metroprolol
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United States of America Patent
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Mar 21, 1995
Grant Date -
N/A
app pub date -
Nov 12, 1993
filing date -
Nov 12, 1993
priority date (Note) -
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Abstract
A sustained release oral solid dosage form of metoprolol pharmaceutical formulation includes a sustained release excipient including a gelling agent, an inert pharmaceutical diluent, a cationic cross-linking agent, and metoprolol provides release of metoprolol for at least about 24 hours. In certain embodiments, the sustained release formulation further includes a hydrophobic material.
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