Melt granulated compositions for preparing sustained release dosage forms
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United States of America Patent
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Apr 4, 1995
Issued Date -
N/A
app pub date -
Mar 31, 1992
filing date -
Mar 4, 1991
priority date (Note) -
In Force
status (Latency Note)
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Abstract
Therapeutically active sustained release dosage forms are described which are prepared from compositions which comprise (A) a hydrophilic cellulose ether polymer or mixtures thereof as a binder matrix material, (B) a granulating medium selected from the group consisting of a lipid component, polyethylene glycol polymers, and mixtures thereof, said granulating medium having a melting range higher than about 30.degree. C., and (C) a therapeutically active medicament, said components being in melt association. The compositions are prepared by a melt granulation process.
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