6-0-methylerythromycin A derivatives
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United States of America Patent
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Apr 4, 1995
Grant Date -
N/A
app pub date -
May 20, 1993
filing date -
Nov 28, 1990
priority date (Note) -
Expired
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Abstract
This invention provides 6-O-methylerythromycin A derivatives represented by the following formula ##STR1## (wherein R.sup.1 and R.sup.2 each represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, and A represents a nitrogen atom or a N.fwdarw.O group) and their pharmaceutically acceptable salts. The erythromycin A derivatives have a strong antimicrobial activity against Gram-negative bacteria and have a much stronger activity against Gram-positive bacteria than previously known compounds.
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