US Patent No: 5,404,871

Number of patents in Portfolio can not be more than 2000

Delivery of aerosol medications for inspiration

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ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

Apparatus and methods for delivering an amount of aerosolized medicine for inspiration by a patient in response to the occurrence of appropriate delivery point or points in the patient's detected breath flow. The aerosol medication may be administered as one or more pulses having a pulse width, shape, and frequency that will maximize the respirable fraction of the aerosolized compound being administered. The delivery point or points may be predetermined or determined from a prior inspiratory flow for depositing the selected medication at one or more desired locations in the patient's airway. Determined delivery points are recursively lowered for each inspiratory flow that does not satisfy one of the predetermined and previously lowered threshold. Changes in the patient's breath flow patterns during the course of an aerosolized medication inspiration therapy program may be detected and used to adjust the controlled amount of medication to be delivered in a given administration and/or to inform the patient of the patient's condition or change in condition. The device also may contain a library of administration protocols or operating parameters for different medications and a means for identifying from the canister the medicinal contents of the canister for customizing operation of the apparatus.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ARADIGM CORPORATIONHAYWARD, CA118
MIRIS MEDICAL INCORPORATED, A CORP. OF CAHAYWARD, CA1

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goodman, David E Brookline, MA 17 2428
Rubsamen, Reid M Oakland, CA 95 4686

Cited Art

Patent Info (Count) # Cites Year
 
RIKER LABORATORIES, INC. (5)
4,446,862 Breath actuated devices for administering powdered medicaments 89 1981
4,624,251 Apparatus for administering a nebulized substance 90 1984
4,664,107 Inhalation activatable dispensers 115 1984
4,860,740 Powder inhalation device 85 1987
5,069,204 Inhaler 113 1990
 
THE BENDIX CORPORATION (3)
4,256,017 Differential area electrohydraulic doser actuator 25 1979
4,366,743 Control system for doser actuator 17 1980
4,386,553 Control system for doser actuator 26 1980
 
BESPAK PLC (2)
4,702,400 Aerosol dispensing metering valve 19 1984
4,896,832 Dispensing apparatus for metered quantities of pressurised fluid 68 1988
 
KEY PHARMACEUTICALS, INC. (2)
4,484,577 Drug delivery method and inhalation device therefor 142 1982
4,679,555 Method and apparatus for intrapulmonary delivery of heparin 31 1984
 
THE JOHNS HOPKINS UNIVERSITY (2)
4,790,305 Medication delivery system 129 1986
4,926,852 Medication delivery system phase one 141 1988
 
YAMAHA CORPORATION (2)
2003/0023,649 Digital filtering method and device and sound image localizing device 1 2002
2003/0023,649 Digital filtering method and device and sound image localizing device 1 2002
 
ACKRAD LABORATORIES, INC. (1)
4,648,393 Breath activated medication spray 87 1984
 
ADVANCED TECHNICAL PRODUCTS, INC. (1)
4,662,537 Timed pill monitor and dispenser 25 1984
 
AKTIEBOLAGET DRACO (1)
4,524,769 Dosage inhalator 142 1982
 
ERICH JAEGER GMBH (1)
4,558,710 Testing of the airways and pulmonary tract of a patient, particularly for sensitivity to aerosols 145 1984
 
ETABLISSEMENTS VALOIS (1)
4,413,755 Metered aerosol valve for use in inverted position 30 1982
 
HEALTHTECH SERVICES CORP. (1)
4,933,873 Interactive patient assistance device 172 1988
 
MAQUET CRITICAL CARE AB (1)
4,819,629 Method and apparatus for delivering aerosol to the airways and/or lungs of a patient 245 1987
 
MARVEN, AL (1)
4,469,255 Automatic and adjustable valving mechanism 20 1982
 
MCINTOSH; KENNETH B. (1)
4,942,544 Medication clock 86 1989
 
MICRO CARE CORPORATION (1)
4,682,713 Pressurized fluid remote-dispenser and assembly including the same 19 1985
 
MOULDING, THOMAS S., JR. (1)
4,604,847 Medicine package, method of opening the package, and machine for performing the method 109 1983
 
PURITAN-BENNETT CORPORATION (1)
4,932,402 Inspiration oxygen saver 71 1987
 
R. J. REYNOLDS TOBACCO COMPANY (1)
4,922,901 Drug delivery articles utilizing electrical energy 175 1988
 
ROBERTS; JOSEPHINE A. (BETHESDA, MD) (1)
4,805,609 Pressurized ventilation system for patients 73 1987
 
S.P.A. VALVOLE AEROSOL RESEARCH ITALIANA -V.A.R.I. (1)
4,427,137 Metering valve for dispensing pressurized liquids 31 1981
 
SCHERING CORPORATION (1)
4,291,688 Inhalation device 86 1979
 
SIERRA BIOTECHNOLOGY COMPANY, L.C. (1)
4,984,158 Metered dose inhaler biofeedback training and evaluation system 260 1988
 
SVEN-ERIK NILSSON (1)
4,934,358 Device for self-administration of physiologically active substances, with prevention of overdosing 113 1988
 
THERMO JARRELL ASH CORPORATION (1)
4,361,401 Automatic sample deposition in flameless analysis 58 1980
 
TRITEC INDUSTRIES, INC. (1)
4,462,398 Respirating gas supply method and apparatus therefor 78 1982
 
TRUDELL MEDICAL LIMITED (1)
4,534,343 Metered dose inhaler 122 1984
 
UNIVERSITY OF AUCKLAND (1)
4,677,975 Method of dispensing and/or a dispenser 295 1985
 
WELLS FARGO BANK, NATIONAL ASSOCIATION (1)
4,832,012 Intermittent signal actuated nebulizer 42 1987
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (6)
4,576,157 Oral inhalation apparatus 52 1983
4,592,348 Aerosol inhaler 56 1984
4,745,925 Optoelectronic inhalation sensor for monitoring inhalation and for inhalation therapy 47 1986
4,803,978 Apparatus for actuating an inhaler 47 1987
4,852,582 Method and kit for measuring the effectiveness of bronchodilators 30 1987
5,133,343 Apparatus for supporting an inhaler 39 1988

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
RESMED LIMITED (82)
6,123,071 Facial masks for assisted respiration or CPAP 77 1996
6,112,746 Nasal mask and mask cushion therefor 197 1997
6,240,921 Automated stop/start control in the administration of CPAP treatment 22 1997
6,253,764 Control of delivery pressure in CPAP treatment or assisted respiration 24 1997
6,152,129 Determination of leak and respiratory airflow 56 1997
D428987 Nasal mask shell 40 1997
D423096 Nasal mask cushion 48 1997
6,138,675 Determination of the occurrence of an apnea 48 1997
6,532,957 Assisted ventilation to match patient respiratory need 34 1997
6,123,082 Device for preventing or reducing the passage of air through the mouth 26 1997
6,029,665 Determination of patency of airway 37 1997
6,332,463 Flow estimation and compensation of flow-induced pressure swings in CPAP treatment and assisted respiration 26 1997
6,494,207 Harness assembly for a nasal mask 59 1997
6,044,844 Mask and harness assembly 114 1997
6,213,119 Inspiratory duration in CPAP or assisted respiration treatment 42 1997
6,029,660 Substance delivery apparatus 52 1997
6,091,973 Monitoring the occurrence of apneic and hypopneic arousals 80 1997
6,119,693 Forehead support for facial mask 193 1998
6,367,474 Administration of CPAP treatment pressure in presence of APNEA 45 1998
6,237,592 Auto-calibration of pressure transducer offset 19 1998
6,561,190 Mask and a vent assembly therefor 54 1998
6,119,723 Apparatus for varying the flow area of a conduit 6 1998
6,237,593 Estimation of flow and detection of breathing CPAP treatment 10 1998
6,182,657 Pressure control in CPAP treatment or assisted respiration 13 1998
D421298 Flow generator 54 1998
6,336,454 Nasal ventilation as a treatment for stroke 10 1998
6,397,841 Apparatus for supplying breathable gas 31 1998
6,216,691 Mounting body 13 1998
6,513,526 Full-face mask and mask cushion therefor 78 1999
6,357,441 Nasal mask and mask cushion therefor 121 1999
6,561,191 Mask and a vent assembly therefor 26 1999
6,363,270 Monitoring the occurrence of apneic and hypopneic arousals 58 1999
6,990,977 Substance delivery apparatus 4 1999
6,279,569 Determination of leak and respiratory airflow 21 2000
6,634,358 Nasal mask cushion assembly 27 2000
6,463,931 Forehead support for facial mask 62 2000
6,526,974 Pressure control in CPAP treatment or assisted respiration 11 2000
6,776,155 Nasal ventilation as a treatment for stroke 5 2001
6,871,649 Nasal mask cushion assembly 8 2001
6,581,602 Nasal mask and mask cushion therefor 62 2002
7,178,527 Nasal mask and mask cushion therefor 7 2002
6,688,307 Methods and apparatus for determining instantaneous elastic recoil and assistance pressure during ventilatory support 13 2002
7,036,508 Harness assembly for a nasal mask 21 2002
6,557,556 Forehead support for facial mask 26 2002
6,701,927 Full-face mask and mask cushion therefor 48 2002
6,810,876 Assisted ventilation to match patient respiratory need 36 2002
6,691,708 Forehead support for facial mask 37 2002
6,860,269 Forehead support for facial mask 37 2002
7,845,354 Mask and vent assembly therefor 2 2002
6,973,929 Forehead support for a facial mask 8 2002
D498529 Portion of a cushion for use with a mask assembly in the application of continuous positive airway pressure (CPAP) 4 2003
7,207,335 Mask and vent assembly therefor 11 2003
7,302,950 Patient interface for respiratory apparatus 7 2003
6,997,188 Forehead support for facial mask 5 2003
7,234,466 Forehead support for facial mask 6 2003
7,069,933 Breathing mask and mask cushion therefor 7 2003
7,320,320 Determination of patency of the airway 2 2003
D550351 Elastic gas washout vent for a respiratory mask 2 2004
7,137,389 Method and apparatus for determining instantaneous inspired volume of a subject during ventilatory assistance 9 2004
7,503,327 Mask with integral cushion and forehead piece 9 2004
7,406,965 Forehead support for facial mask 3 2004
7,243,651 Cushion and mask therefor 5 2004
7,942,150 Nasal assembly 5 2005
7,882,837 Forehead support for facial mask 2 2005
7,779,834 Method and apparatus for substance delivery in system for supplying breathable gas 1 2005
7,644,713 Method and apparatus for determining instantaneous leak during ventilatory assistance 8 2006
7,926,487 Respiratory mask having gas washout vent and gas washout vent assembly for a respiratory mask 3 2006
8,056,561 Full-face mask and mask cushion therefor 0 2006
7,610,916 Forehead support for facial mask 6 2006
8,122,886 Respiratory mask assembly with vent 0 2006
7,931,023 Patient interface assembly for CPAP respiratory apparatus 3 2007
7,950,392 Cushion and mask therefor 0 2007
7,730,886 Determination of patency of the airway 0 2007
7,762,259 Mask with integral cushion and forehead piece 2 2007
7,942,149 Forehead support for a facial mask 2 2009
8,186,348 Forehead support for facial mask 2 2009
8,051,853 Method and apparatus for providing ventilatory assistance 3 2009
8,360,060 Distinguishing between closed and open airway apneas and treating patients accordingly 0 2010
8,210,180 Mask with integral cushion and forehead piece 2 2010
8,397,716 Method and apparatus for substance delivery in system for supplying breathable gas 0 2010
8,381,722 Distinguishing between closed and open airway apneas and treating patients accordingly 0 2010
8,353,294 Respiratory mask assembly 0 2011
 
ARADIGM CORPORATION (47)
5,522,385 Dynamic particle size control for aerosolized drug delivery 122 1994
5,542,410 Delivery of aeerosol medications for inspiration 53 1994
5,622,162 Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval 53 1995
5,957,124 Dynamic particle size control for aerosolized drug delivery 162 1995
6,098,620 Device for aerosolizing narcotics 69 1995
5,960,792 Device for aerosolized delivery of peptide drugs 165 1995
5,934,272 Device and method of creating aerosolized mist of respiratory drug 173 1995
5,915,378 Creating an aerosolized formulation of insulin 135 1995
5,655,516 Delivery of aerosol medications for inspiration 21 1996
5,906,202 Device and method for directing aerosolized mist to a specific area of the respiratory tract 73 1996
5,743,250 Insulin delivery enhanced by coached breathing 116 1996
5,755,218 Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval 103 1996
5,829,436 Ventilation imaging using a fine particle aerosol generator 26 1997
5,888,477 Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin 29 1997
5,829,435 Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles 43 1997
5,884,620 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 46 1997
5,813,397 Delivery of aerosol medication for inspiration 50 1997
5,855,564 Aerosol extrusion mechanism 35 1997
5,792,057 Ventilation imaging using a fine particle aerosol generator 30 1997
6,131,567 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 43 1998
6,192,882 Formulation and devices for monitoring the efficacy of the delivery of aerosols 44 1998
6,085,753 Insulin delivery enhanced by coached breathing 37 1998
6,098,615 Method of reproducibly effecting a patient's glucose level 37 1998
5,970,973 Method of delivering insulin lispro 50 1998
5,873,358 Method of maintaining a diabetic patient's blood glucose level in a desired range 16 1998
6,024,090 Method of treating a diabetic patient by aerosolized administration of insulin lispro 16 1998
5,941,240 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 44 1998
5,971,951 Aerosol extrusion mechanism 34 1998
7,244,714 Methods of delivering aerosolized polynucleotides to the respiratory tract 0 1999
6,167,880 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 60 1999
6,354,516 Pore structures for reduced pressure aerosolization 14 1999
6,408,854 Insulin delivery enhanced by coached breathing 23 2000
6,250,298 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 38 2000
6,431,166 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 20 2001
6,349,719 Formulation and devices for monitoring the efficacy of the delivery of aerosols 16 2001
6,427,681 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 5 2001
6,688,304 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 11 2001
6,431,167 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 6 2001
6,689,986 Pore structures for reduced pressure aerosolization 4 2001
6,732,954 Pore structures for reduced pressure aerosolization 0 2002
6,647,987 Insulin delivery enhanced by coached breathing 3 2002
7,021,309 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 2 2003
7,028,686 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 9 2003
6,855,909 Pore structures for reduced pressure aerosolization 1 2003
7,316,360 Pore structures for reduced pressure aerosolization 1 2004
7,448,375 Method of treating diabetes mellitus in a patient 1 2005
7,490,603 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 0 2005
 
UNIVERSIDAD DE SEVILLA (23)
6,196,525 Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber 16 1998
6,197,835 Device and method for creating spherical particles of uniform size 47 1998
6,189,803 Fuel injection nozzle and method of use 46 1998
6,187,214 Method and device for production of components for microfabrication 38 1998
6,174,469 Device and method for creating dry particles 38 1998
6,116,516 Stabilized capillary microjet and devices and methods for producing same 51 1998
6,119,953 Liquid atomization process 49 1999
6,386,463 Fuel injection nozzle and method of use 7 2000
6,299,145 Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber 6 2000
6,234,402 Stabilized capillary microjet and devices and methods for producing same 34 2000
6,241,159 Liquid atomization procedure 8 2000
6,464,886 Device and method for creating spherical particles of uniform size 6 2001
6,357,670 Stabilized capillary microjet and devices and methods for producing same 20 2001
6,394,429 Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber 8 2001
6,432,148 Fuel injection nozzle and method of use 5 2001
6,405,936 Stabilized capillary microjet and devices and methods for producing same 7 2001
6,554,202 Fuel injection nozzle and method of use 6 2002
6,557,834 Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber 3 2002
6,792,940 Device and method for creating aerosols for drug delivery 3 2002
6,595,202 Device and method for creating aerosols for drug delivery 9 2002
7,059,319 Device and method for creating aerosols for drug delivery 1 2004
7,059,321 Device and method for creating aerosols for drug delivery 1 2004
7,293,559 Device and method for creating aerosols for drug delivery 0 2005
 
NOVARTIS PHARMA AG (9)
6,138,668 Method and device for delivering aerosolized medicaments 58 1997
6,681,767 Method and device for delivering aerosolized medicaments 24 2000
6,543,448 Apparatus and methods for dispersing dry powder medicaments 33 2000
6,546,929 Dry powder dispersing apparatus and methods for their use 14 2001
7,300,919 Pulmonary delivery of active fragments of parathyroid hormone 5 2002
6,901,929 Dry powder dispersing apparatus and methods for their use 4 2002
7,628,978 Stabilized preparations for use in metered dose inhalers 3 2003
7,422,013 Dry powder dispersing apparatus and methods for their use 2 2005
8,336,545 Methods and systems for operating an aerosol generator 0 2007
 
NOVARTIS AG (8)
7,871,598 Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use 0 2000
8,168,223 Engineered particles and methods of use 0 2001
7,306,787 Engineered particles and methods of use 9 2002
7,521,069 Methods and compositions for pulmonary delivery of insulin 6 2003
8,404,217 Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use 0 2005
8,161,969 Dry powder dispersing apparatus and methods for their use 0 2008
8,246,934 Respiratory dispersion for metered dose inhalers comprising perforated microstructures 0 2010
8,349,294 Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use 0 2010
 
RENOPHARM LTD. (6)
7,968,575 Nitric oxide donors and uses thereof 0 2005
7,579,477 Thiazole-based nitric oxide donors having alkyl substituent(s) and uses thereof 0 2005
7,498,445 Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof 0 2005
7,368,577 Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof 2 2005
7,332,513 Thiazole-based nitric oxide donors having acyl substituent(s) and uses thereof 0 2005
8,134,010 Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof 0 2008
 
HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (5)
6,830,046 Metered dose inhaler 7 2002
6,886,557 Inhalation device and method for delivering variable amounts of different components 5 2002
7,481,213 Medicament dispenser 0 2004
7,467,630 Medicament dispenser 0 2004
7,530,352 Inhalation device and method for delivering variable amounts of different components 2 2004
 
INVACARE CORPORATION (5)
7,290,546 Nasal mask 8 2003
7,621,274 Nasal mask 9 2003
D507831 Nasal mask 6 2004
D583931 Nasal mask 0 2004
8,028,698 Breathing mask 0 2007
 
MICRODOSE THERAPEUTX, INC. (5)
6,923,979 Method for depositing particles onto a substrate using an alternating electric field 4 1999
6,428,809 Metering and packaging of controlled release medication 9 1999
6,702,683 Metering and packaging of controlled release medication 6 2002
7,404,968 Metering and packaging of controlled release medication 8 2004
7,632,533 Method and apparatus for producing uniform small portions of fine powders and articles thereof 0 2007
 
MANNKIND CORPORATION (4)
7,464,706 Unit dose cartridge and dry powder inhaler 4 2003
8,156,936 Unit dose capsules and dry powder inhaler 0 2007
8,215,300 Unit dose cartridge and dry powder inhaler 1 2008
8,424,518 Dry powder inhaler and system for drug delivery 0 2009
 
RESMED R&D GERMANY GMBH (4)
7,100,610 Breathing mask for feeding a breathing gas to a mask user and discharge device for discharging breathing gas 6 2001
7,000,614 Breathing mask arrangement and a forehead support device for same 17 2002
7,320,323 Breathing mask device and application device and frontal support device thereof 12 2002
8,371,301 Breathing mask for feeding a breathing gas to a mask user and discharge device for discharging breathing gas 0 2010
 
MAP MEDIZIN-TECHNOLOGIE GMBH (3)
7,654,263 Breathing mask arrangement and a forehead support device for same 3 2005
7,967,014 Application device for breathing mask arrangement 1 2006
7,992,559 Breathing mask arrangement as well as an application device and a forehead support device for same 2 2007
 
QUADRANT DRUG DELIVERY LIMITED (3)
7,785,631 Solid dose delivery vehicle and methods of making same 0 2005
7,780,991 Solid dose delivery vehicle and methods of making same 0 2005
7,744,925 Solid dose delivery vehicle and methods of making same 0 2005
 
ACTIVAERO GMBH (2)
7,766,012 Device for the controlled inhalation of therapeutic aerosols 3 2001
7,077,125 Apparatus for administering aerosols 4 2002
 
EP SYSTEMS SA (2)
7,694,892 Liquid droplet plug and spray system 1 2005
8,016,209 Liquid droplet plug and spray system 0 2005
 
OMRON HEALTHCARE CO., LTD. (2)
6,651,650 Ultrasonic atomizer, ultrasonic inhaler and method of controlling same 34 1994
6,901,926 Ultrasonic atomizer, ultrasonic inhaler and method of controlling same 5 2003
 
PROTEUS DIGITAL HEALTH, INC. (2)
8,419,638 Body-associated fluid transport structure evaluation devices 0 2008
8,332,020 Two-wrist data gathering system 0 2011
 
RESPIRONICS (UK) LTD. (2)
7,451,760 Controlling drug delivery apparatus 0 2001
7,748,382 Inhalation method and apparatus 2 2003
 
SENSORMEDICS CORPORATION (2)
6,435,175 Pulmonary drug delivery device 26 2000
6,615,825 Pulmonary drug delivery device 1 2002
 
AGRAMEX CONSULTANTS LIMITED (1)
6,223,744 Wearable aerosol delivery apparatus 65 1999
 
ASTRA AKTIEBOLAG (1)
D377686 Training device for inhaler 5 1994
 
BABY'S BREATH LTD. (1)
6,877,509 Aerosol inhalation interface 0 2002
 
BATTELLE MEMORIAL INSTITUTE (1)
7,607,435 Gas or liquid flow sensor 2 2004
 
CANON KABUSHIKI KAISHA (1)
7,856,975 Liquid medicine ejection device 0 2006
 
CAREFUSION 205, INC. (1)
7,007,696 Mask cushion and method of using same 19 2002
 
CENTOCOR, INC. (1)
7,833,531 Method for treating insulin sensitivity by long-acting GLP-1 receptor mimetibody agonists 0 2007
 
CNA DEVELOPMENT LLC (1)
7,718,176 Human EPO mimetic hinge core mimetibodies, compositions, methods and uses 0 2009
 
COVIDIEN LP (1)
8,335,992 Visual indication of settings changes on a ventilator graphical user interface 0 2009
 
DRUCK LIMITED (1)
5,579,244 Pressure controller 21 1995
 
FLOW PHARMA, INC. (1)
6,450,189 Method and device for production of components for microfabrication 15 2000
 
FOSS, WALTER W. (1)
7,051,735 Interactive pressure support system and method 3 2003
 
HILL-ROM SERVICES PTE. LTD (1)
8,251,876 Breathing exercise apparatus 0 2008
 
INJET DIGITAL AEROSOLS LIMITED (1)
8,201,554 Inhalation device having an optimized air flow path 0 2009
 
INO THERAPEUTICS GMBH (1)
7,861,717 Controlled gas-supply system 4 2003
 
IVAX CORPORATION (1)
7,331,340 Medicament dispensing device with a display indicative of the state of an internal medicament reservoir 20 2004
 
JONES MEDICAL INSTRUMENT COMPANY (1)
5,724,986 Casing and spirometer for metered dose inhaler 18 1995
 
MAP-MEDIZINTECHNOLOGIE GMBH (1)
7,775,209 Breathing mask for feeding a breathing gas to a mask user and discharge device for discharging breathing gas 3 2006
 
MPEX PHARMACEUTICALS, INC. (1)
8,357,696 Aerosolized fluoroquinolones and uses thereof 0 2010
 
NEW WATER PRODUCTS, LLC (1)
5,766,487 Method of visually indicating the ability of a filter element to remove particulates 3 1996
 
NORTH CAROLINA STATE UNIVERSITY (1)
7,900,625 Inhaler system for targeted maximum drug-aerosol delivery 1 2006
 
ONEIDA RESEARCH SERVICES, INC. (1)
5,676,129 Dosage counter for metered dose inhaler (MDI) systems using a miniature pressure sensor 62 1996
 
RIC INVESTMENTS, LLC. (1)
8,042,537 Method of providing interactive pressure support 2 2006
 
SIEMENS AKTIENGESELLSCHAFT (1)
6,394,353 Medical device with control arangement for a device component 6 1998
 
SMITHKLINE BEECHAM CORPORATION (1)
6,990,975 Medicament delivery system 5 2000
 
SOLAR SHIELD CORPORATION (1)
6,029,659 Inhalation device with counter 66 1995
 
UNIVERSITY OF SHEFFIELD OF WESTERN BANK (1)
6,739,332 Inhalers 0 2001
 
WESTMED, INC. (1)
6,202,642 Electronic monitoring medication apparatus and method 119 1999
 
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (1)
7,378,438 Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders 0 2003
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (3)
5,839,430 Combination inhaler and peak flow rate meter 59 1997
8,439,033 Inhalation device 0 2008
8,443,294 Visual indication of alarms on a ventilator graphical user interface 0 2010